Cell TransplantationStem cell-based cell therapy for spinal cord injury. Kim BG,Hwang DH,Lee SI,et al. Cell Transplantation . 2007Kim BG, Hwang DH, Lee SI, Kim EJ, Kim SU. Stem cell-based cell therapy for spinal cord injury. Cell Transplant. 2007;16(4): 355-364....
Traumatic spinal cord injury (SCI) results in direct and indirect damage to neural tissues, which results in motor and sensory dysfunction, dystonia, and pathological reflex that ultimately lead to paraplegia or tetraplegia. A loss of cells, axon regeneration failure, and time-sensitive ...
Injury and disease of the spinal cord are generally met with a poor prognosis. This poor prognosis is due not only to the characteristics of the diseases but also to our poor ability to deliver therapeutics to the spinal cord. The spinal cord is extremel
Stem Cell Research & Therapy volume 3, Article number: 24 (2012) Cite this article 18k Accesses 11 Altmetric Metrics details Abstract Injury and disease of the spinal cord are generally met with a poor prognosis. This poor prognosis is due not only to the characteristics of the diseases but...
Mesenchymal stem cell therapy for spinal cord injury Traditionally, the regenerative capacity of MSCs was thought to be related to its plasticity to differentiate into neural and glial cells [26,27]. However, recent studies suggested that the therapeutic effect is mostly exerted by their paracrine ...
Induced pluripotent stem cell technology for spinal cord injury: a promising alternative therapy mainly discusses the problems regarding stem cell therapy for spinal cord injury, including the characteristics and action modes of all relevant cell types. ... Yu,PP Li,B Shen,... - 《Neural Regenera...
Cellular therapy for spinal cord injury (SCI) is overviewed focusing on bone marrow mononuclear cells, olfactory ensheathing cells, and mesenchymal stem cells. A case is made for the possibility of combining cell types, as well as for al... TE Ichim,F Solano,F Lara,... - 《International ...
Stem cell therapy is a potential treatment for spinal cord injury (SCI), and a variety of different stem cell types have been evaluated in animal models an... Vibhu,Sahni,A John,... - 《Nature Reviews Neurology》 被引量: 253发表: 2010年 Stem cell-based cell therapy for spinal cord inj...
作者以MSC的三种来源,bone marrow (BM), adipose tissue (AT), or the umbilical cord (UC)以及特性,从临床试验的角度心血管、呼吸、生殖和皮肤等领域进行荟萃分析,并就免疫学、信号通路等机制进行了总结。 hypothesis—— BM-MSCs are potentially good candidates for brain and spinal cord injury treatment, ...
Spinal cord injuriesremain without any specific therapy. Despite initial optimism from trials, neuroprotective molecules and poorly defined stem cells have not provided satisfactory controlled therapies. The European project 'From stem cell technology to functional restoration after spinal cord injury' (Rescu...