This has been partially overcome by the development of 3-dimensional (3D) in vitro models, one of which is the spheroid assay or 3D sprouting assay that exploits the effect of the extracellular matrix to endothelial cell functions. This chapter focuses on the description of the spheroid assay ...
Cell Invasion in the Spheroid Sprouting Assay: A Spatial Organization Analysis Adaptable to Cell Behaviour. PLoS One 2014, 9, e97019.Blacher S, Erpicum C, Lenoir B et al (2014) Cell invasion in the spheroid sprouting assay: a spatial organisation analysis adaptable to cell behaviour. Plos ...