Primary binding receptors, many of which have been disclosed in various mammals, are localized throughout the acrosomal region of the sperm surface. A panel of monoclonal antibodies against proteins from the sperm surface was prepared. Antibodies were screened by immunofluorescence for protein ...
Sperm express a range of cell surface proteins and receptors, possibly including major histocompatibility complexes (MHC), and at least some of the sperm RNAs seem to be linked to cell surface products 30, 31, 32, 33. Additionally, the cell surface odour receptors could in principle help sperm...
The Molecular Chaperone HSPA2 Plays a Key Role in Regulating the Expression of Sperm Surface Receptors That Mediate Sperm-Egg Recognition 2012, PLoS ONE Composition and Significance of Detergent Resistant Membranes in Mouse Spermatozoa 2009, Journal of Cellular Physiology New insights into the molecular...
Among mammals, sperm first make contact with eggs at the surface of the egg extracellular coat, or zona pellucida (ZP). This contact can lead to species-specific binding of sperm to eggs via sperm receptors located in the ZP. Bound sperm then undergo changes that enable them to penetrate ...
展开 关键词: Animals Humans Spermatozoa Sea Urchins Recombinant Proteins Heat-Shock Proteins Receptors, Cell Surface Restriction Mapping Cloning, Molecular Fertilization DOI: 10.1126/science.8383878 被引量: 315 年份: 1993 收藏 引用 批量引用 报错 分享 全部...
It appears that the sperm surface receptor(s) mediating progesterone action is different from the intracellular progesterone receptor that mediates the steroid’s genomic effects (Baldi et al., 1991...Sabeur K, Edwards DP & Meizel S 1996 Human sperm plasma membrane progesterone receptors and the ...
NPR2 is located on the flagellar midpiece of spermatozoa. Typically, chemoattractants bind to sperm surface receptors26,32,33. NPPC acts locally as an autocrine and paracrine regulator via natriuretic pep- tide receptor 2 (NPR2), a guanylyl cyclase-coupled receptor30,34. The levels of ...
The switch is a protein receptor that responds to the female sex hormoneprogesterone, which is released by the egg or oocyte, the ultimate goal toward whichspermswim. Thousands of these receptors sit on the surface of a sperm's tail and when the sperm gets close to the egg, the hormone ...
The endpoint of in vitro/in vivo capacitation is the ability of sperm surface receptors to bind to their complementary ligands on pellucida, the that surro... DRP Tulsiani,HT Zeng,A Abou-Haila - 《Society of Reproduction & Fertility Supplement》 被引量: 194发表: 2007年 Effect of cooling ...
Whereas fertilin, a mammalian sperm surface protein, is involved in this crucial interaction, sperm receptors on the egg plasma membrane have not been identified. Because fertilin contains a predicted integrin ligand domain, we investigated the expression and function of integrin subunits in un...