Rheumatology An immunofluorescence pattern that may be seen when the human epithelial cell line, HEp-2, is stained with serum from patients with connective tissue diseases, especially SLE, but also mixed connective tissue disease (MCTD), sicca syndrome, Sjögren syndrome, polymyositis, rheumatoid art...
Background The clinical significance of Dense Fine Speckled (DFS) pattern Anti-nuclear antibodies (ANA) by indirect immunofluorescence method (IIF) is unclear and has been inversely associated with rheumatic disease 1 2.Objectives Our purpose was to determine associations between DFS pattern ANA and ...
Thomas K. Burnham and D'Anne M. KleinsmithSeminars in Arthritis and RheumatismBurnham, T.K. and Kleinsmith, D.M. (1983) . The "true speckled" antinuclear antibody (ANA) pattern its tumultaous history . Semin. Arth. Rheum. 13 : 155-159....
2007. Relevance of the immunofluorescence pattern for interpretation of the ANA test: the case of the dense fine speckled pattern. Rev Assoc Med Brasil 53: 439-445.Dellavance A; Leser PG,Andrade LE; Relevance of the immunofluorescence pattern for interpre tation of the ANA test-the case of ...
Basu A, Woods-Burnham L, Ortiz G et al (2015) Specificity of antinuclear autoantibodies recognizing the dense fine speckled nuclear pattern: preferential targeting of DFS70/LEDGFp75 over its interacting partner MeCP2. Clin Immunol 161:241-250...
Basu A, Woods-Burnham L, Ortiz G, Rios-Colon L, Figueroa J, Albesa R, Andrade LE, Mahler M, Casiano CA (2015) Specificity of antinuclear autoantibodies recognizing the dense fine speckled nuclear pattern: preferential targeting of DFS70/LEDGFp75 over its interacting partner MeCP2...