Background The clinical significance of Dense Fine Speckled (DFS) pattern Anti-nuclear antibodies (ANA) by indirect immunofluorescence method (IIF) is unclear and has been inversely associated with rheumatic disease 1 2.Objectives Our purpose was to determine associations between DFS pattern ANA and ...
Twitter Google Share on Facebook Imaging Image texture The background ‘canvas’ on which different echoes in an ultrasonogram are painted Rheumatology An immunofluorescence pattern that may be seen when the human epithelial cell line, HEp-2, is stained with serum from patients with connective tissu...
View all citing articles on Scopus☆ Presented in part at the 41st Annual Meeting of the American Academy of Dermatology, New Orleans, Louisiana, December 7, 1982. 1 From the Department of Dermatology, Henry Ford Hospital, Detroit, Mich....
Background Antinuclear antibodies (ANA) positivity with a dense fine speckled (DFS) pattern by indirect immunofluorescence (IIF), as per the definition of the International Consensus on ANA Patterns (ICAP), is not uncommon and is linked ... JM Lpez-Ortega,Sánchez-Herrero,N Esta-Capell,... ...
ThedetectionofU1-n-RNPantibodiesinbloodandCSFaswellasspeckledimmunofluorescencepatternarediagnostic. U1的检测氮核糖核蛋白在血液和脑脊液以及斑点免疫荧光抗体诊断模式。 Speckledalongthewaysweatandwisdom,beautyandachievementswasbehindhis back. 汗水和智慧洒满沿途,美丽和成就写在身后。
Nuclear dense fine speckled (DFS) pattern, a competent-level pattern evaluated by the ICAP previously (AC-02),2 is frequently discussed in the current recommendation for it being the pattern best associated with apparently healthy individuals, or negatively correlating with systemic autoimmune rheumatic...
Based on the recommendation of the International Consensus on ANA Patterns (ICAP),2 the recognition of a nuclear DFS pattern is not to be taken as the same as the determination of an anti-DFS70 antibody using a follow-up specific immunoassay. In fact, HEp-2 IIFA is a screening test for...
In particular, autoantibodies associated with the dense fine speckled (DSF) ANA-Hep-2 pattern, has been largely detected in apparently healthy individuals. Methods ANA-Hep-2 test from 921 children aged 0.2 to 13.9 years was retrospectively retrieved from the routine of a large private laboratory ...
Indirect immunofluorescence cytoplasmic patternImmunofluorescence on HEp2-cells is the standard diagnostic assay for the detection of anti-nuclear antibodies (ANA). Cytoplasmic speckled patterns are a common finding, and are associated with various antibodies, including anti-synthetase antibodies. However, ...
Methods A retrospective study of 425 patients from a university health care system with a positive ANA-DFS pattern consecutively between August 2017 and September 2018. Sera samples underwent ANA testing by IIF on HEp-2 cell substrates (Euroimmun, Germany). Clinical information was retrieved from ...