Speckle-type poz protein is negatively associated with malignancies and inhibits cell proliferation and migration in liver cancer. Tumor Biol. 2015; 36 (12):9753–9761.Huang Y, Tan N, Jia D,et al. Speckle-type POZ protein is nega-tively associated with malignancies and inhibits cell ...
Speckle-type POZ proteinMatrix metalloproteinase 2Signaling pathwayBACKGROUND: Elevated expression of matrix metalloproteinases (MMPs) is correlated with invasion and metastasis of colorectal cancer (CRC). Recently, a previous study has suggested that speckle-type POZ protein (SPOP) could inhibit cancer ...
speckle-type POZ protein (SPOP), regulates TWIST1 in breast cancer remains unknown. In this study, we report that SPOP physically interacts with, ubiquitinates, and destabilizes TWIST1. SPOP promotes K63-and K48-linked ubiquitination
英文名称: Speckle-Type POZ Protein Human Recombinant 总访问: 269 国产/进口: 进口 半年访问: 24 产地/品牌: prospec 产品类别: 细胞生物学试剂 规格: PRO-195 最后更新: 2024-12-5 货号: CAS 号: 参考报价: 询价 立即询价 电话咨询 [发表评论] [本类其他产品] [本类其他供应商] [收藏] 分享...
Abstract Speckle-type POZ protein (SPOP) is an adaptor of the cullin 3-based ubiquitin ligase responsible for the degradation of oncoproteins frequently overexpressed in many tumor cells. Altered expression and somatic mutations of SPOP have been observed in various tumor types with chromosomal aberrati...
However, although the important role of ELK3 in tumor progression is well-known, the molecular mechanisms involved in the regulation of ELK3 protein degradation through ubiquitination remain largely unknown. Speckle-type POZ protein (SPOP) is an adaptor protein of Cullin3 (CUL3)-based ubiquitin ...
Stabilization of Speckle-type POZ Protein (Spop) by Daz Interacting Protein 1 (Dzip1) Is Essential for Gli Turnover and the Proper Output of Hedgehog Signaling.Stabilization of Speckle-type POZ Protein (Spop) by Daz Interacting Protein 1 (Dzip1) Is Essential for Gli Turnover and the Proper ...
Identification of speckle-type POZ protein somatic mutations in African American prostate cancer 体细胞突变前列腺癌POZ蛋白肿瘤抑制基因前列腺肿瘤鉴别非洲点缀类型 POZ 蛋白质(SPOP ) 是在前列腺癌症(PCa ) 的肿瘤 suppressor.SPOP 体的变化在欧洲降下的那些的多达 15% PCa 被报导了.然而,在非洲的美国人(AA ...
Speckle-type POZ protein mutations interrupt tumor suppressor function of speckle-type POZ protein in prostate cancer by affecting androgen receptor degradation 雄激素受体基因突变前列腺癌POZ抑制功能蛋白降解斑点定序研究的大规模 exome 揭示了染色体的区域,它贡献这学习的抵抗前列腺癌症(CRPC ) phenotype.1,2...
Speckle-type POZ proteinMatrix metalloproteinase 2Signaling pathwayElevated expression of matrix metalloproteinases (MMPs) is correlated with invasion and metastasis of colorectal cancer (CRC). Recently, a previous study has suggested that speckle-type POZ protein (SPOP) could inhibit cancer cell ...