It explores the three parts of the analysis which divides the discussion of the cancers, 10 cancers from bladder to kidney cancer in part 1 and all other cancers in parts 2 and 3. It says that 6.6 million Americans had lost their lives due to cancer, which implies that the government ...
Most cancer driver genes are involved in generic cellular processes such as DNA repair, cell proliferation and cell adhesion, yet their mutations are often confined to specific cancer types. To resolve this paradox, we explained mutation frequencies of s
A new study from USC Norris Comprehensive Cancer Center, part of Keck Medicine of USC, suggests that the regioncancerspreads to in the brain may not be random, but rather, is dependent on where the cancer originated in the body. "We discovered that different types of cancer are more likely...
link transcription factors to target genes that are conditionally activated in specific types or subtypes of cancer. their results have suggested that alterations in pathways that active some transcription factors might be responsible for the observed gene deregulation and cancer pathogenesis. segal et al...
Transcriptional heterogeneity among malignant cells of a tumor has been studied in individual cancer types and shown to be organized into cancer cell states; however, it remains unclear to what extent these states span tumor types, constituting general features of cancer. Here, we perform a pan-ca...
This is aspecificfor cancer. 这是一种治疗癌症的特效药. 《简明英汉词典》 This disease isspecificto this area. 这种疾病只发生在这一地区. 《简明英汉词典》 There are twospecific( al ) questions we must answer. 有两个具体问题我们必须回答. ...
This analysis also found more fungal reads in all cancer types than in negative controls (Data S1.1D). In the TCGA cohort, we observed significant, cancer type-specific differences in the percentage of classified fungal, bacterial, and pan-microbial reads of the total or unmapped reads (Data ...
Molecular Insight in Gastric Cancer Induction: An Overview of Cancer Stemness Genes Gastric cancer is one of the most outgoing human cancers in the world. Two main functional types were described: Intestinal adenocarcinoma and diffuse one... H Akhavan-Niaki,AA Samadani - 《Cell Biochemistry & ...
Transposable elements (TE) are repetitive genomic elements that harbor binding sites for human transcription factors (TF). A regulatory role for TEs has been suggested in embryonal development and diseases such as cancer but systematic investigation of t
Metastatic gastric carcinoma is a highly lethal cancer that responds poorly to conventional and molecularly targeted therapies. Despite its clinical relevance, the mechanisms underlying the behavior and therapeutic response of this disease are poorly und