miscellaneous cell typesnervous system cancersarcomasPracticing veterinarians can more readily address oncology on a clinical basis by placing tumors within five major group divisions. By understanding cancer cell types within the construct of these major group divisions, the diagnosis, management, ...
Thus, DNA damage caused by overexpression of ORF2 proteins may induce genotoxic stress and apoptosis14. It has been proposed that LINE-1 hypomethylation and activation may play a causative role in urothelial carcinogenesis by inducing genetic instability which accompanies cancer progression, especially ...
Historically, the primary focus of cancer research has been molecular and clinical studies of a few essential pathways and genes. Recent years have seen the rapid accumulation of large-scale cancer omics data catalysed by breakthroughs in high-throughput technologies. This fast data growth has given...
Growth is a generic term that describes processes in which the mass of a body changes over time. In biology, the problem of growth is fundamental to all aspects of life, with realizations as diverse as cell division, morphogenesis, development, maintenance, cancer, and aging. DOI: 10.1007/978...
We present a comprehensive report on the facts and trends of breast cancer in Korea in 2013. Data on the newly diagnosed patients in the year 2013 were collected from 99 hospitals by using nationwide questionnaire survey. Clinical characteristics such as stage of cancer, histologic types, ...
Plasma membrane (PM) ion channels contribute to virtually all basic cellular processes and are also involved in the malignant phenotype of cancer cells. He... N Prevarskaya,R Skryma,Y Shuba - 《Trends in Molecular Medicine》 被引量: 470发表: 2010年 Dominant Forms of Economic Organization in...
Links between human papillomaviruses (HPVs) and cervical cancer were first suspected almost 30 years ago. DNA of specific HPV types has since been found in almost all cervical cancer biopsies. HPV oncogenes that are expressed in these cells are involved in their transformation and immortalization,...
Cancer Cell Line Encyclopedia(癌症细胞系百科全书,CCLE)的动机主要是为了帮助科学家们更好地理解肿瘤生物学,特别是了解人类肿瘤细胞在分子水平上的异质性。CCLE项目旨在通过收集、分类、描述和共享大量不同肿瘤类型的细胞系信息,以促进癌症研究的进展和发展个性化医疗。CCLE项目的一个主要目标是通过细胞系的基因组学、...
Identification of a novel function of TWIST, a bHLH protein, in the development of acquired taxol resistance in human cancer cells. Taxol is one of the widely used chemotherapeutic drugs against many types of human cancer. While it is considered as one of the most effective anticancer d... ...
Effort invested in the development of new drugs often fails to be translated into meaningful clinical benefits for patients with cancer. The development of more effective anticancer therapeutics and accurate prediction of their clinical merit remain urge