The TMA was analyzed by the AQUA® method of immunofluorescent analysis using antibodies to Ki67, p53 and Estrogen Receptor (ER) as controls and antibodies to phospho-Erk (p-ERK), phospho-AKT(p-AKT) and phospho-tyrosine (p-tyr) as the test set. The second cohort was analyzed as whole...
Antisera in Immunoassays with special Reference to Monoclonal Antibodies to Human Immunoglobulins When antisera are raised by the conventional means of injection of immunogen in adjuvant into animals, the antibodies are derived from many responding clones of cells and are consequently heterogeneous in struc...
Dr. William Hewson who often has been designated as one of the Fathers of Hematology noted that the red cells were flat rather than globular and also described the leukocytes for the first time and showed that coagulation occurred in the plasma (3). The last of the formed elements of the ...
In a neutrally charge state, LysoTracker probes can freely diffuse across intact plasma membranes of live cells. Due to the inherently acidic properties within the lysosome, upon diffusion into the lysosome the weakly basic moiety is protonated. In this charged state, the probe does not readily ...
The incidence of these OS autoantibodies was not increased in patients with NOS autoimmune diseases with the exception of thyroglobulin antibodies, which were significantly more frequent in RA ( P <0.001) and in Sjgren's syndrome ( P <0.05) patients than in normal controls. Investigation of 169...
In a neutrally charge state, LysoTracker probes can freely diffuse across intact plasma membranes of live cells. Due to the inherently acidic properties within the lysosome, upon diffusion into the lysosome the weakly basic moiety is protonated. In this charged state, the probe does not readily ...
Antibodies are currently the fastest growing class of therapeutic proteins. When antibody fragments are included, there are over thirty-five antibody-based medicines approved for human therapy. Many more antibody and antibody-like fragments are being eva
CRT antibodies have been developed enabling the localization of creatine uptake sites in the brain, retina, muscle and other tissues. These tools in conjunction with the use of appropriate cell models should allow further progress in our knowledge on the regulation and cellular trafficking of the ...
In a neutrally charge state, LysoTracker probes can freely diffuse across intact plasma membranes of live cells. Due to the inherently acidic properties within the lysosome, upon diffusion into the lysosome the weakly basic moiety is protonated. In this charged state, the probe does not readily ...
Techniques for determining mucosubstances, however, can be of considerable value in separating Crohn's disease from other conditions. Studies on the distribution of lymphocytes and plasma cells using selective antibodies to human immunoglobulins are practicable and likely to be of value. Close co-...