Importantly, B cells can present cognate tumour-derived antigens to T cells, with the functional consequences of such interactions being shaped by the B cell phenotype. Furthermore, the isotype and specificity of the antibodies produced by plasma cells can drive distinct immune responses. Here we ...
The present invention relates to a method for producing an antibody, to an antibody specifically reacting with plasma cells, to genes which encode such antibodies, to antigens which are labeled by such an antibody, to additional antibodies directed against said antigens and to methods for ...
Plasma cell, short-lived antibody-producing cell derived from a type of leukocyte (white blood cell) called a B cell. B cells differentiate into plasma cells that produce antibody molecules closely modeled after the receptors of the precursor B cell. Onc
Antibodies against plasma cells 专利名称：Antibodies against plasma cells 发明人：HANS KONRAD MULLER-HERMELINK,AXEL GREINER,BERND DORKEN,RALF BARGOU,PETER KUFER 申请号：AU2369101 申请日：20001222 公开号：AU2369101A 公开日：20010709 专利内容由知识产权出版社提供 摘要：The present invention relates to a...
Plasma cells are specialized immune cells that produce antibodies. They develop from activated B cells. Latest Research and Reviews CD27 is not an ideal marker for human memory B cells and can be modulated by IL-21 upon stimulated by Anti-CD40 Shuangpeng Kang Qiongli Wu Changyou Wu Research...
Related to Plasma cells:Macrophages,Histiocytes,Memory cells n. Any of various short-lived cells that develop from activated B cells and secrete large numbers of antibodies. They are found chiefly in the bone marrow, spleen, and lymph nodes. Also calledplasmacyte. ...
Antibody responses to viral infections are sustained for decades by long-lived plasma cells (LLPCs). However, LLPCs have yet to be characterized in humans. Here we used CD19, CD38, and CD138 to identify four PC subsets in human bone marrow (BM). We found that the CD19−CD38hiCD138...
B cells are implicated in the etiology of multiple sclerosis (MS). Intrathecal IgG synthesis, cerebrospinal fluid (CSF) oligoclonal bands and lesional IgG deposition suggest a role for antibody-mediated pathology. We examined the binding of IgG1 monoclonal recombinant antibodies (rAbs) derived from ...
[A]: B-cells are responsible for antibody me- diated immunity which directly recognize an antigen and give rise to antibody secreting plasma cells and memory 8-cells. [R]: Immunity can be induced by using vac- cines for long- lived active period. View Solution Antibodies produced in th...
Plasma cells(PC) are terminally differentiated and nondividingimmune cellsarising from B cells whose primary function is to secrete antibodies to fight infection.1–3PCs can live for a long period, even a lifetime, in the bone marrow if survival signals, such as interleukin (IL)-6, A prolif...