Antibodies are secreted immunoglobulin molecules produced mainly by plasma cells. The antigen-binding site of the antibody has a unique structure that allows it to bind antigen in a highly specific manner. Latest Research and Reviews Validation of a multiplexed immunoassay for immunological analysis of...
The invention relates to methods of producing antibodies, including monoclonal antibodies, comprising culturing a limited number of plasma cells. It also relates to methods of identifying antibodies by performing assays on the antibodies produced by the cultured plasma cells to determine their function, ...
B cells are implicated in the etiology of multiple sclerosis (MS). Intrathecal IgG synthesis, cerebrospinal fluid (CSF) oligoclonal bands and lesional IgG deposition suggest a role for antibody-mediated pathology. We examined the binding of IgG1 monoclonal recombinant antibodies (rAbs) derived from ...
aengieer 正在翻译,请等待... [translate] a约翰经常与他的老板发生争执 正在翻译,请等待... [translate] amanoeuvre and reverse 调动和反面 [translate] aPlasma cells produce antigen-specific antibodies that are work against antigen. 正在翻译,请等待... [translate] ...
Plasma cells are key to the immune response because they secrete antibodies. Given that antibodies are made of protein in which membrane-enclosed cell organelle would be expected the plasma cell top has in abundance. Why? What is the function of lymphocytes in th...
Antibodies against plasma cells 专利名称：Antibodies against plasma cells 发明人：HANS KONRAD MULLER-HERMELINK,AXEL GREINER,BERND DORKEN,RALF BARGOU,PETER KUFER 申请号：AU2369101 申请日：20001222 公开号：AU2369101A 公开日：20010709 专利内容由知识产权出版社提供 摘要：The present invention relates to a...
Monoclonal antibodies are increasingly used to prevent and treat viral infections and are pivotal in pandemic response efforts. Antibody-secreting cells (ASCs; plasma cells and plasmablasts) are an excellent source of high-affinity antibodies with therap
Long-lived plasma cells: a mechanism for maintaining persistent antibody production. Curr. Opin. Immunol. 10, 252–258 (1998). Article CAS PubMed Google Scholar Scheid, J. F. et al. Differential regulation of self-reactivity discriminates between IgG+ human circulating memory B cells and ...
Antibodies are produced by the body's B cells to fight off infections by bacteria, viruses, and other invasive pathogens. When an individual B cell recognizes a specific pathogen-derived "antigen" molecule, it can proliferate and develop intoplasma cellsthat secrete large amounts of antibody capab...
Syntaxin-4 is implicated in the secretion of antibodies by human plasma cells PCs are responsible for the production and secretion of antibodies, the effector molecules of the humoral immune response. The molecular mechanisms respons... - 《Journal of Leukocyte Biology》 被引量: 0发表: 2014年 ...