Most breast cancers are sensitive to estrogen (or, as doctors say, “estrogen-receptor-positive” or “ER-positive,”) which means that estrogen fuels their growth. “So there was a fear that soy could act as estrogen in the body and stimulate cancer cells,” Meyers says. “It was ...
emerging mechanisms of how isoflavones, such as genistein, interact with processes leading to breast cancer.Findings – The key finding of this analysis is that these mechanisms include a multitude of contrasting effects of genistein on estrogenic and non‐estrogenic signaling pathways controlling cell ...
The inverse association was evident among women with either estrogen receptor–positive or –negative breast cancer and was present in both users and nonusers of tamoxifen. Conclusion Among women with breast cancer, soy food consumption was significantly associated with decreased risk of death and ...
Hsieh CY, Santell RC, Haslam SZ, Helferich WG (1998 Sep 1) Estrogenic effects of genistein on the growth of estrogen receptor-positive human breast cancer (MCF-7) cells in vitro and in vivo. Cancer Res 58(17):3833–3838. Erratum in: Cancer Res 1999 Mar 15;59(6):1388 Google Scholar...
I was treated at Duke Medical Center and was instructed to avoid ALL soy products due to my breast cancer being estrogen positive. Many people have no idea about phytoestrogen. Soy is in so many things these days and often disguised under various names including lecithin. I have several ...
More than 70 percent of the 1.67 million women diagnosed with breast cancer worldwide in 2012 was estrogen-receptor positive, and tamoxifen and other endocrine therapies meant to reduce the ability of estrogen to promote cancer growth, are the most common drugs used for these cancers. Although en...
ER, estrogen receptor; ER–, estrogen receptor–negative; ER+, estrogen receptor–positive; LACE, Life After Cancer Epidemiology Study; MET-h, metabolic equivalent task hours; NA, not applicable; PR, progesterone receptor; PR–, progesterone receptor–negative; PR+, progesterone receptor–positive;...
For years, one of the things that breast cancer survivors have been the most fearful of is soybeans and soy products. Somehow many years ago there came the belief that soy because it contains “phytoestrogens”, could stimulate the recurrence of breast cancer. The word estrogen has scared ever...
Due to the weak estrogen-like activity of soy isoflavones, there is concern that high doses of isoflavones may not be safe in post-menopausal women withestrogen receptor-positive breast cancerand may also slightly increase the risk ofuterine cancer. For more information, see theConcerns and Cauti...
Sakamoto T, Horiguchi H, Oguma E, Kayama F (2010) Effects of diverse dietary phytoestrogens on cell growth, cell cycle and apoptosis in estrogen-receptor-positive breast cancer cells. J Nutr Biochem 21(9):856–864 ArticleCASGoogle Scholar ...