Disopyramide prolonged refractoriness in the infarct zone, measured by analysis of electrograms from an implanted "composite" electrode, by 38 to 53%, depending on the mode of pacing. These values were significantly greater than the increase produced by disopyramide in ventricular effective refractory ...
Inducibility was considered unchangedif VT/VF was initiated by the same mode of stimulation as during the control study. 1.4. Drug administration. The initial dosage of d,l-sotalol was 80 mg orally every 12 h for the 1st 24 to 48 h. Dosage was then increased in stepwise fashion to up ...