Conventional genetic mapping methods are designed for single-gene traits. As such, they are inadequate to study quantitative polygenic traits. Consequently, genetic analysis of affected sibling pairs or families is hampered by multiple modes of inheritance of the trait, genetic heterogeneity, and large...
(Applied Biosystems). DNA Sequences were analysed with Lasergene 7 (DNAStar, Madison, WI, USA) and aligned by using the ClustalW option of the MegAlign program. The clones were used to amplify the probes for FISH usingTaqDNA polymerase (Invitrogen) and purified using Wizard® SV Gel and...
NOTICE: input file contains 4 rs identifiers, output file contains information for 4 rs identifiers WARNING: 1 rs identifiers have multiple records (due to multiple mapping) and they are all written to output [kaiwang@biocluster ~/]$ cat snplist.avinput chr2 186229004 186229004 C T rs...
Using a local high-density SNP map, we also mapped a third mutation to a resolution of approximately 2 kb, sufficient to localize the mutation within a single gene. These methods should accelerate the rate of positional cloning in Drosophila.Berger...
Description: A web tool that provides pre-estimated effective sample sizes, specific to each minor ...
1 根据公司提供的snp坐标信息调取对应的基因。如果公司给你的snp数据是.vcf的格式,上网搜搜vcf2gene或者...
similar to those of Kazakh cattle. The genomic homozygosity of Xinjiang inbred cattle is significantly higher than other populations; the inbreeding depression is observed in body size to a certain extent because body size decreased when corresponding homozygosity increased. Totally, six basic bio-...
Gene mapping in the wild with SNPs: guidelines and future directions One of the biggest challenges facing evolutionary biologists is to identify and understand loci that explain fitness variation in natural populations. This... J Slate,J Gratten,D Beraldi,... - 《Genetica》 被引量: 292发表: ...
mapping function. If markers from different homologs are mapped together (as if they were on the same homolog), gaps of ~40 cM are therefore expected between different homologous chromosomes; such gaps were identified and used to separate the homologs. Each parental map is expected to have a...
The aim of this work was to construct a high-resolution genetic map for the dissection of complex morphological and agronomic traits in Chinese cabbage (Brassica rapa L. syn. B. campestris). Chinese cabbage, an economically important vegetable, is a good