(2000) How many diseases does it take to map a gene with SNPs? Nature Genet., 26, 151±157.Weiss KM, Terwilliger JD (2000) How many diseases does it take to map a gene with SNPs? Nat Genet 26:151-157Weiss, K.M. and Terwilliger, J.D. (2000), `How many diseases does it ...
When making a phylogeny of a gene, it is often of interest to find out which conserved or functional domains of the gene were present in the ancestral species, and most of the time you will know what species or group of species you want to investigate. For example, if you are ...
Note it is advised to not use any form of spaces in the gene file other than the tab delimitations to separate the column. The next query region's information will occupy the next line. In this manner, you can specify an unlimited list of regions to be analyzed by CATE. Asample gene ...
Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in motor control, stable mood, and autonomic function. SNPs in this gene may be associated with some neuropsychiatric conditions, including schizophrenia, borderline syndrome, and others, ...
Computational tools have been tested for different purposes to study cancer and polyploidy [133,134]. Among these approaches, we would like to highlight studies on nucleotide polymorphisms (SNPs), structural variants (SVs), unique somatic tumor-specific variants [135], genome annotation, mutation ...
Advances in forensics are giving us an unprecedented ability to solve cases—and exposing mistakes in some investigations.
In female cells, a process called X-chromosome inactivation (XCI) occurs, where one of the two X chromosomes in each cell is switched off to equalize X chromosome dosage with males. This process is regulated by a gene calledXIST, which produces a long non-coding RNA. XIST helps to form...
In agro-ecosystem, plant pathogens hamper food quality, crop yield, and global food security. Manipulation of naturally occurring defense mechanisms in hos
The advent of large-scale genomic data has proved crucial to furthering know- ledge of the evolution of humankind and subsequent diffusion out of Africa. The recently published HapMap Phase II harbours over three million single nucleotide polymorphisms (SNPs) typed in four distinct human ...
How are genes added to the gene pool? How does cloning affect the gene pool? How can the bottleneck effect influence the gene pool? How often do mutations occur in a gene pool? How is a gene pool like a pool of genes? What is a closed gene pool? How to find a gene pool? How ...