The beads are randomly allocated to a microarray and each bead type is typically represented at multiple locations on the array. Therefore each SNP is measured with a certain amount of redundancy. On each bead, 50-bp oligonucleotide probes bind to the sequence directly adjacent to an SNP ...
such as cDNA, expression, exon, SNP, array-CGH and ChIP-on-chip. It converts the data into ...
Class to represent SNP annotation for a microarrayNick Cooper
array-CGH and ChIP-on-chip. It converts the data into standard formats that can be visualized ...
Whole-genome resequencing of 84 individual clam samples and 277 pooled clam libraries yielded over 305 million SNPs, which were filtered down to a set of 370,456 SNPs that were used as input for the design of a 66K SNP array. This medium-density array features 66,543 probes targeting codi...
35 Ling J, Zhuang G, Tazon-Vega B et al: Evaluation of genome coverage and fidelity of multiple displacement amplification from single cells by SNP array. Mol Hum Reprod 2009; 15: 739–747. 36 Treff NR, Levy B, Su J, Northrop LE, Tao X, Scott Jr RT: SNP microarray-based 24 ...
and knowledge driven methods, and delivering professional-grade results. We are most familiar with human genomics projects, but have experience with other organisms as well. We are most focused on supporting sequencing projects, but are very capable of supporting array and PCR-based projects as ...
Both assays are based on Illumina’s Bead Chip technology, which involves direct hybridization of whole-genome amplified genomic DNA to a bead array of 50-mer locus-specific primers12,13,14, an enzymatic-based extension assay, a sandwich-based immunohistochemistry assay, and the final imaging by...
Aston E, Whitby H, Maxwell T, Glaus N, Cowley B, Lowry D, Zhu XL, Issa B, South ST, Brothman AR: Comparison of targeted and whole genome analysis of postnatal specimens using a commercially available array based comparative genomic hybridisation (aCGH) microarray platform. J Med Genet. 200...
This SNP microarray uses known nucleotide sequences as probes to hybridize with the tested DNA sequences, allowing a qualitative and quantitative SNP analysis. Data quality control was performed using Genome Studio. The call rate cut-off was 98% as it an off-the-shelf array. Statistical and ...