Imaging markers of small vessel disease (SVD) (white matter hyperintensities [WMH] on structural MRI, visual scores and volume; perivascular spaces; lacunes and microbleeds), and vascular risk measures were assessed in both cohorts. We assessed associations between retinal and brain measurements using...
Cerebral small vessel disease (cSVD) causes lacunar ischemic stroke (25% of ischemic strokes), vascular dementia, and neuropsychiatric and mood disorders and impairs mobility.1,2 Despite this disease burden, there is no specific treatment for cSVD.3,4 Although patients with lacunar ischemic stroke ...
Ischemic bowel can lead to gut translocation of bacteria , necrosis , and perforation . Gangrenous small bowel with closed-loop obstruction caused by an omental band adhesion Image:“Intra-operative photograph” by the Department of Surgery, Hinchingbrooke Hospital, Hinchingbrooke Healthcare NHS Trust,...
Cerebral small vessel disease is a major cause of stroke and dementia, but its genetic basis is incompletely understood. We perform a genetic study of three MRI markers of the disease in UK Biobank imaging data and other sources: white matter hyperintens