Imaging markers of small vessel disease (SVD) (white matter hyperintensities [WMH] on structural MRI, visual scores and volume; perivascular spaces; lacunes and microbleeds), and vascular risk measures were assessed in both cohorts. We assessed associations between retinal and brain measurements using...
Cerebral small vessel disease is a major cause of stroke and dementia, but its genetic basis is incompletely understood. We perform a genetic study of three MRI markers of the disease in UK Biobank imaging data and other sources: white matter hyperintens
Cerebral small vessel disease (cSVD) causes lacunar ischemic stroke (25% of ischemic strokes), vascular dementia, and neuropsychiatric and mood disorders and impairs mobility.1,2 Despite this disease burden, there is no specific treatment for cSVD.3,4 Although patients with lacunar ischemic stroke ...
With this hypothesis, the air pollution effect would not need to be preferentially associated with small vessel disease stroke as ischemic stroke caused by air pollutants could affect large and small arteries alike but the resulting clinical picture would tend to be that of a mild stroke. We ...
Risk of ischemic heart disease in women after radiotherapy for breast cancer. N Engl J Med. 2013;368(11):987–98. https://doi.org/10.1056/nejmoa1209825. Article CAS PubMed Google Scholar Dess R, Sun Y, Matuszak M, Sun G, Soni P, Bazzi L, et al. Cardiac events after radiation ...