Small vessel ischemic disease is a common mechanism for stroke. The underlying vasculopathy is due to exposure to chronic risk factors like hypertension and diabetes. This chapter will review the diagnosis and management of small vessel disease and discuss how it differs from intracranial ...
Late-onset sporadic Alzheimer’s disease (LOAD) and small vessel ischemic disease (SVID) frequently influence each other and co-exist in the aging brain depicting a clinical, neuroradiological and neuropathological spectrum defined as ‘mixed dementia’. Although mixed dementia represents the second ...
It has also been used to measure the residual neurological deficit at the chronic stage after ischemic events. However, the value of NIHSS in ischemic cerebral small vessel disease has not been specifically evaluated. The purpose of this study was to investigate the link between the NIHSS score ...
Cerebral small vessel disease (SVD) is commonly observed on neuroimaging among elderly individuals and is recognized as a major vascular contributor to dementia, cognitive decline, gait impairment, mood disturbance and stroke. However, clinical symptoms are often highly inconsistent in nature and severity...
Chronic small vessel disease (SVD) has been shown to disrupt this network’s integrity and has been proposed as a predictor of poor outcome after stroke. We studied this hypothesis in patients with acute ischemic stroke of the striatocapsular region, an area of pronounced cortical and ...
small vessel disease Acronyms Any of multiple small cerebral infarcts in the corona radiata, internal capsule, striatum, thalamus, basis pontis, and/or cerebellum, occasionally preceded by transient symptoms, due to occlusion or stenosis of small penetrating branches of the middle and posterior cerebral...
Vascular cognitive impairment and dementia (VCID) is commonly caused by vascular injuries in cerebral large and small vessels and is a key driver of age-related cognitive decline. Severe VCID includes post-stroke dementia, subcortical ischemic vascular d
Cerebral small vessel disease can be identified using magnetic resonance imaging, and includes white matter hyperintensities, lacunar infarcts, cerebral microbleeds, and brain atrophy. Cerebral small vessel disease and chronic kidney disease share many risk factors, including hypertension. This study aims ...
Cerebrovascular disease is a major burden to individuals and their communities worldwide. Stroke is one of the leading causes of death and disability, and the prevention and treatment of stroke can be improved with a better understanding of its causation. Cerebral small vessel disease (SVD) is a...
RAGE-TLR crosstalk sustains chronic inflammation in neurodegeneration. Mol. Neurobiol. 55, 1463–1476 (2018). Article CAS Google Scholar Bath, P. M. & Wardlaw, J. M. Pharmacological treatment and prevention of cerebral small vessel disease: a review of potential interventions. Int. J. Stroke...