Definition Cerebral small vessel ischemic disease (SVID) results from compromised functioning of the small penetrating cerebral arteries, causing reduced blood flow to deep white matter regions of the brain, leading to focal lacunar infarcts, diffuse ischemia (leukoaraiosis), vascular cognitive ...
CONCLUSIONS: Cerebral small vessel disease, with or without a history of cerebrovascular disease, is associated with increased risk of death and ischemic stroke in patients with atherosclerotic disease. 展开 关键词: Humans Cerebrovascular Disorders Brain Ischemia Magnetic Resonance Imaging Risk Factors ...
We investigated relations between cerebral small vessel disease (cSVD) markers and evolution of the ischemic tissue from ischemic core to final infarct in people with acute ischemic stroke treated with intravenous thrombolysis. Data from the Stroke Imaging Repository (STIR) and Virtual International Strok...
Circadian Rhythms Predict Small Vessel Ischemic Disease.The author comments on the article "Cerebral small vessel disease is related to disturbed 24-h activity rhythms: A population-based study," by L. A. Zuurbier and colleagues. Topics discussed include the importance of circadian rhythm for ...
Cerebral small vessel disease can be identified using magnetic resonance imaging, and includes white matter hyperintensities, lacunar infarcts, cerebral microbleeds, and brain atrophy. Cerebral small vessel disease and chronic kidney disease share many risk factors, including hypertension. This study aims ...
It has also been used to measure the residual neurological deficit at the chronic stage after ischemic events. However, the value of NIHSS in ischemic cerebral small vessel disease has not been specifically evaluated. The purpose of this study was to investigate the link between the NIHSS score ...
Meaning These 2 inexpensive licensed medications (ISMN and cilostazol) may reduce adverse long-term outcomes of lacunar ischemic stroke, a form of cerebral small vessel disease, and definitive trials are needed to confirm these findings.Abstract Importance...
Conclusions and Relevance Intensive BP lowering did not reduce cerebral perfusion in severe small vessel disease. Trial Registration isrctn.org Identifier: ISRCTN37694103 Introduction Cerebral small vessel disease (SVD) causes 20% of all ischemic strokes1 and is the most common cause of vascular cogniti...
Conclusion Frontal lobe atrophy in ischemic stroke patients may be associated with small vessel disease. The association between WMLs and FLA was predominant over atrophy of the parietal and temporal lobes, which suggests that the frontal lobe may be vulnerable to subcortical ischemic changes.Yangkun ...
Meaning This study found that a novel sequence variation event was associated with COL4A1 polyadenylation signals usage and severe CSVD through dysregulation of this major vascular matrisome gene, suggesting diagnostic and therapeutic implications. Abstract Importance Cerebral small vessel di...