Ischemic small vessel disease (SVD) is a common finding on routine scans in older people, but cognitive sequelae vary considerably. To improve understanding of mechanisms underlying decline or preservation of cognitive function in this condition, we assessed cognition and cortical plasticity in 20 ...
Developing TLF in these patients would be catastrophic, considering the longer life expectancy at risk for recurrent ischemic events [6, 7]. A retrospective cohort study that enrolled 1574 patients with acute coronary syndrome who underwent successful stent implantation revealed an improved predictive ...
Lastly, to evaluate their effect on established AKI, changes in plasma creatinine were evaluated during the first week of corticosteroid treatment. The median day of symptom duration was calculated for corticosteroid treatment initiation. This was used as the starting point of the seven days in the...
Retinal whitening and vessel changes may be specific to malaria as they seem to be caused by sequestered parasitized erythrocytes; sequestration occurs similarly in the retinal and cerebral microcirculation. The number of hemorrhages observed on admission seems to be correlated with the Glasgow score ...
elderly patients with dementia-related psychosis, migraine, myoclonus, neuroleptic malignant syndrome, paresthesia, post-traumatic neck syndrome, seizures, serotonin syndrome, sinus headache, sleep walking/somnambulism, speech disorder, stroke, syncope, tension headache, tic, transient ischemic attack, ...
showed that ischemic changes included a cytosolic change in xanthine oxido-reductase, which does not influence mitochondrial reactive oxygen species, and a huge increase in succinate, which is an intermediate in the mitochondrial citric acid cycle [44]. They went on to show that this hypoxic ...
Transfer of convalescent plasma (CP) had been proposed early during the SARS-CoV-2 pandemic as an accessible therapy, yet trial results worldwide have been mixed, potentially due to the heterogeneous nature of CP. Here we perform deep profiling of SARS-C
More interestingly, our results showed changes in monocyte subset distributions at earlier stages of disease, before the onset of ischemic injury to tissues. A significantly increased percentage of intermediate CD14++CD16+ monocytes occurred in patients with ischemic rest pain compared to intermittent ...
Frequency of Subclinical Lacunar Infarcts in Ischemic Leukoaraiosis and Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencepha... BACKGROUND AND PURPOSE: Small vessel cerebrovascular disease is an important cause of vascular cognitive impairment. It is usually sporadic but also...
MI was defined by cardiac biomarker elevation with at least 1 value above the 99th percentile of the upper reference limit, with concomitant ischemic symptoms or electrocardiographic findings indicative of ischemia unrelated to an interventional procedure. TLR was defined as any repeat PCI of the ...