Only 1 subject was found not to have any retinopathy, despite having observable Fazekas grade I white matter hyperintensity (WMH) lesions under MRI. Onthe other hand, 25 of the respondents were found to have observable WMH under MRI, 10 had lacunar infarcts and 8 had cerebral atrophy...
24-h blood pressure and small vessel diseases are independently associated with cognitive impairment in lacunar infarct patients Yasumasa Yamamoto1, Tomoyuki Ohara1, Yoshinari Nagakane1, Eijiro Tanaka1, Fukiko Morii1, Takashi Koizumi1 and Ichiro Akiguchi2 Although the relationships between chronic kidne...
The Fazekas scale [31] was used to grade the presence of WMHs, where a score of ≥ 2 was considered pathological and representative of pathological presence of WMHs. Lacunar infarcts were defined as having ≥ 1 ischemic infarction (< 1.0 cm) in the deep white matter, the basal ...
However, the relationship between late-life blood pressure changes and progression of CSVD remains elusive. Previous research has established a correlation between elevated blood pressure and cerebral small vessel disease (CSVD). Elevated BP variation was associated with a wide range of subclinical brain...
With the increase of Fazekas' grade,plasma Hcy levels increase in turn among LA patients( P 0. 05). Conclusion Plasma Hcy is correlated with cerebral SVD,especially SBI,LA,is an independent risk factors of cerebral SVD,but not found to be obviously associated with cerebral large vessel ...
1 lacunes, ≥ 1 cerebral microbleeds, moderate to severe (grade 2–4) EPVS in basal ganglia or the centrum of the oval, periventricular WMH Fazekas 3 (extending into deep white matter) and/or deep WMH 2–3 (early confluent)....
small vessel disease in VCI are microhemorrhages. However, while computed tomography and magnetic resonance imaging are able to detect morphologic lesions, these modalities cannot determine functional consequences of the underlying pathological changes, which can be detected and quantitatively assessed by ...
Blood pressure variability is related to faster cognitive decline in ischemic stroke patients: PICASSO subanalysis Association between total cerebral small vessel disease score and cognitive function in patients with vascular risk factors Introduction ...
small vessel disease; vascular damage; blood–brain barrier damage; reactive oxygen species; endothelial dysfunction; metalloproteinases1. Introduction Small vessel disease (SVD) (also called cerebral small vessel disease, cSVD) relies on the deep brain’s small vessels alterations. Small vessels are ...
Among the participants in this cohort, healthy controls (with WMH Fazekas grade ≤2 only) were randomly selected (1:1) using software (SPSS Inc., Chicago, IL, USA) after matching by age (+/−2 years) and gender (Figure 1). Cerebral amyloid angiopathy (CAA), heritable CSVD, and AD ...