(2017). Impact of small vessel disease in the brain on gait and balance. Scientific Reports, 7, 41637. https://doi.org/10.1038/ srep41637Pinter D, Ritchie SJ, Doubal F, Gattringer T, Morris Z, Bastin ME, del C.
Small-vessel disease Brain Ischemic stroke Hemorrhage Vascular dementia 1. Anatomy of cerebral small vessels Small blood vessels include arterioles, capillaries, and venules [1]. They are found ubiquitously throughout the human body, including the brain and heart [2]. These small vessels have been...
The single-variant association test identified 3 common variants with a likely protective effect on small vessel ischemic disease (0.54>OR>0.32, adj. p-value 1, adj. p-val<0.05) together with,cluster andduring brain hypoperfusion and their overexpression correlated with the ischemic lesion size. ...
small vessel cerebral disease with or without ocular anomalies caused by COL4A1 mutations, is likely an underrecognized cause of perinatal stroke. The pattern of abnormalities reported herein should prompt strong consideration for diagnosis and molecular testing....
Purpose This study aims to investigate the alterations of brain volumetry and associated structural covariance at lobar level in cerebral small-vessel disease (CSVD) with and without cognitive impairment. Method Twenty-seven CSVD patients with mild cognitive impairment (CSVD-MCI), 37 CSVD patients ...
Cerebrovascular disease is a major burden to individuals and their communities worldwide. Stroke is one of the leading causes of death and disability, and the prevention and treatment of stroke can be improved with a better understanding of its causation. Cerebral small vessel disease (SVD) is a...
Small vessel disease (SVD; arteriolosclerosis) is a widespread cause of lacunar stroke and vascular dementia and is characterized by fibrosis and depletion of vascular myocytes in small penetrating arteries. Vascular endothelial growth factor (VEGF) is associated with brain aging, and Immunolabeling ...
Loss of white matter integrity is associated with gait disorders in cerebral small vessel disease. Brain 134 (1), 73–83. http://dx.doi.org/10.1093/brain/ awq34321156660. De Leeuw, F.E., de Groot, J.C., Achten, E., Oudkerk, M., Ramos, L.M., Heijboer, ...
Cerebral small vessel disease (CSVD) plays an important role in cognitive impairment, stroke, disability, and death. Hypertension is the main risk factor for CSVD. The use of antihypertensive therapy has not resulted in the expected decrease in CSVD complications, which may be related to the unde...
Cerebral small vessel diseases (cSVD) are responsible for 20-30% of stroke events. They represent a leading cause of vascular cognitive impairment and dementia developing with aging. During the past 3 decades, beside the frequent sporadic forms of SVD related to current vascular risk factors...