Cerebral small vessel disease (cSVD) is a prevalent condition in aging that affects the brain's small arteries, arterioles, venules, and capillaries. It often manifests as abnormalities on brain imaging, such as white matter hyperintensities (WMHs), lacunes, cerebral microbleeds (CMBs), or ...
Truncating mutations in murine Col4A1 result in cerebral hemorrhage in both neonatal and adult mice, and mutations have been reported in infants with congenital porencephaly, fetal IVH, and adults with cerebral small vessel disease (35,76). More recently, mutations have also been reported in ...
Brain, 135 (2012), pp. 2506-2514 Google Scholar 12 Georgescu M.M., Pinho Mda C., Richardson T.E., Torrealba J., Buja L.M., Milewicz D.M., Raisanen J.M., Burns D.K. The defining pathology of the new clinical and histopathologic entity ACTA2-related cerebrovascular disease Acta Neu...
A, alveolar septa; B, bronchiole; BV, blood vessel; DPBS, Dulbecco’s phosphate-buffered saline; PFU, plaque-forming unit. Syrian Golden Hamsters Inoculated with SARS-CoV-2 Develop Progressive Broncho-Interstitial Pneumonia with Prominent Vascular Lesions SARS-CoV-2–induced airway disease and ...
Whether white matter lesion (WML) is associated with vascular cognitive impairment in cerebral small vessel disease (CSVD) remains controversial; some severe CSVD patients retain normal cognitive function, and cortical thinning associated with WMLs has also been recently reported. The contribution of cort...
Frequency not reported: Constipation, difficulty swallowing, dry mouth, dysphagia, gastroesophageal reflux disease (GERD/GORD), tongue protrusion Postmarketing reports: HiccupsAripiprazole Extended/Prolonged-Release IM Suspension: Very common (10% or more): Constipation (up to 10%) Common (1% to 10%...
Frequency not reported: Constipation, difficulty swallowing, dry mouth, dysphagia, gastroesophageal reflux disease (GERD/GORD), tongue protrusion Postmarketing reports: HiccupsAripiprazole Extended/Prolonged-Release IM Suspension: Very common (10% or more): Constipation (up to 10%) Common (1% to 10%...
[2]. sPE can cause serious complications in pregnant women and fetuses, including cardiovascular and cerebrovascular disease, disseminated intravascular coagulation, placental abruption, eclampsia, and postpartum hemorrhage (PPH) [3–5]. Of these, there is substantial evidence that sPE can cause an ...
Endovascular access to the sensorimotor cortex offers an alternative to BCI technologies, where electrodes are placed in or on the dura by open-brain surgery. Safety and feasibility data from the first in-human study indicate that it is possible to record neural signals from a blood vessel, and...
Measurement of circulating ST2 and/or IL-33 concentrations is useful for the prognostic evaluation of subjects, in particular for the prediction of adverse clinical outcomes, e.g., mortality, and the detection of severe disease.Inventors: Snider, James V. (San Diego, CA, US) Jacobson, Sven...