Small molecules in targeted cancer therapy: advances, challenges, and future perspectivesDue to the advantages in efficacy and safety compared with traditional chemotherapy drugs, targeted therapeutic drugs have become mainstream cancer treatments. Since the first tyrosine kinase inhibitor imatinib was ...
Explore BPS Bioscience’s small molecule cancer therapy targets for advanced research in targeted treatments. Discover our range of compounds designed to inhibit key cancer-related pathways and enhance therapeutic strategies.
Here, the authors discuss the implementation of a cell-based reporter system which may foster the decision-making process to identify the most promising lead-molecules [1]. New targeted therapies in kidney cancer are discussed by Mayrhofer et al. as the treatment landscape has changed dramatically...
Vincent (F.M.H.) de GrootSpringer New YorkV. de Groot, Targeting: Cancer--Small molecules, in: V.J. Stella, R.T. Borchardt, M.J. Hageman, R. Oliyai, H. Maag, J. Tilley (Eds.), Prodrugs: Challenges and rewards Part 2, Springer-AAPS Press, New York, 2007....
Proteolysis targeting chimeras (PROTACs)in ‘beyond rule-of-five’ chemical space: Recent progress and future challenges 2019, Bioorganic and Medicinal Chemistry Letters Show abstract Small molecules in targeted cancer therapy: advances, challenges, and future perspectives 2021, Signal Transduction and Tar...
Novel biomolecules in targeted cancer therapy: a new approach towards precision medicine Sandra Kannampuzha Reshma Murali Balachandar Vellingiri Medical Oncology(2023) New Nano-Silica Supported Basic Ionic Liquids-Catalyzed Multicomponent Synthesis of imidazo [1,2-a] Pyridines Under Solvent-Free Condition...
In present study we have assessed prospects of significant proteins which are known to be targeted by number of small molecules and related drugs for effective treatment of various forms of cancer. Moreover, we also addressed the efficacies of these drugs toward the cancer treatment and future ...
small molecules that target genetic mutations known to play critical roles in progression to metastatic disease and to influence response to targeted therapies... K Niki,R Rafael 被引量: 0发表: 2020年 EGFR-targeting PLGA-PEG nanoparticles as a curcumin delivery system for breast cancer therapy Poo...
To do that, the researchers screened more than 140,000 small molecules from the National Cancer Institute database and identified several small molecules that could effectively target Y397. They then tested all of these molecules and found two that were the most potent at stopping colon cancer-ce...
Small molecules Targeted therapies This article is cited by Comparative assessment of direct and indirect cold atmospheric plasma effects, based on helium and argon, on human glioblastoma: an in vitro and in vivo study Mahdiyeh Bakhtiyari-Ramezani Mojtaba Nohekhan Meysam Nasiri Scientific Reports...