In: Small Molecules in Oncology. Springer, Berlin Heidelberg, pp131‑157, 2010.Quintas-Cardama A, et al., Small Molecules in Oncology. 2010. p. 103-117.: Springer Verlag Berlin Heidelberg.Keller G, Schafhausen P, Brummendorf TH: Bosutinib. In: Small Molecules in Oncology. Springer; 2010...
Small Molecules in Oncology 来自 infona.pl 喜欢 0 阅读量: 43 作者: UM Martens 摘要: Extensive research into the molecular mechanisms of cancer disease has heralded a new age of targeted therapy. In malignant cells, key proteins that are crucial to tumor growth and survival are now being ...
Although many of these are antibodies directed against additional checkpoint proteins, there is an increasing interest in small-molecule immuno-oncology drugs that address intracellular pathways, some of which have recently entered clinical trials. In parallel, small molecules that target pro-tumorigenic ...
B cells may also function as antigen-presenting cells in some instances. Rights and permissions Reprints and permissions About this article Cite this article Adams, J., Smothers, J., Srinivasan, R. et al. Big opportunities for small molecules in immuno-oncology. Nat Rev Drug Discov 14, 603...
on the systemic capillary leak syndrome following granulocyte colony-stimulating factor therapy in a T-lymphoblastic leukemia/lymphoma patient [5]. Overall, a number of highly comprehensive articles providing insight into currently available and new targeted therapies/small molecules in oncology are availabl...
当当书之源外文图书在线销售正版《预订Small Molecules in Oncology [ISBN:9783030082574]》。最新《预订Small Molecules in Oncology [ISBN:9783030082574]》简介、书评、试读、价
small molecules that target genetic mutations known to play critical roles in progression to metastatic disease and to influence response to targeted therapies... K Niki,R Rafael 被引量: 0发表: 2020年 EGFR-targeting PLGA-PEG nanoparticles as a curcumin delivery system for breast cancer therapy Poo...
Key Responsibilities:Lab based associate will design and execute sophisticated cell-based assays and biology experiments that inform drug discovery and/or an in-depth understanding of a small molecule’s mechanism of action.Troubleshoot various cell-base
Small molecules in targeted cancer therapy: advances, challenges, and future perspectivesLei Zhong, Yueshan Li, Liang Xiong, Wenjing Wang, Ming Wu, Ting Yuan, Wei Yang, Chenyu Tian, Zhuang Miao, Tianqi Wang & Shengyong Yang ...
Small molecules were first screened in a cell-free in vitro homogeneous time-resolved fluorescence (HTRF) assay, utilizing αPD-L1 (MIH1) and αPD-1 (nivolumab) antibodies as positive controls. A compound identified as ARB-272572 (compound A) inhibited PD-1/PD-L1 HTRF at 400 pM IC50 ...