891 The Transforming growth factor 尾 (TGF-尾) signaling pathway has been previously known to play a tumor suppressor role in hematologic malignancies. Smad proteins and their phosphorylation play a vital role in TGF-尾 signaling pathway. There are three class of Smads; Receptor-regulated Smads (...
TGF-超家族 TGF-家族 抑制素(inhibit)/活化素(activin)家族 骨形态发生蛋白(bone morphoenetic protein ,BMPs)家族 苗勒管抑制物(MIS)/AMH(antimullerian hormone) 胶质细胞系来源的神经营养因子(glialcellin 2、e-derived neurotrophic factor,GDNF)等。TGF-的生物学特性 经内源性蛋白酶如弗林蛋白酶(furin)...
protein phosphorylation pattern specification process heart development negative regulation of gene expression skeletal system development osteoblast differentiation negative regulation of protein phosphorylation positive regulation of catenin import into nucleus negative regulation of protein catabolic process protein ...
牙本质涎蛋白通过整合素β6调节Smad蛋白活性 牙本质涎蛋白通过整合素β6调节S m a d蛋白活性 勾晓辉柴纪华袁国华* (武汉大学口腔医学院,湖北省口腔基础医学重点实验室 省部共建国家重点实验室培育基地,口腔生物医学教育部重点实验室湖北武汉430079)[摘要]目的:研究牙本质涎蛋白片段D S P a a183-219与成牙本质...
Target Protein:phospho-Smad2/Smad3 (Thr8) IR:Immunogen Range:PF(p-T)PP Clonality:Polyclonal Isotype:IgG Entrez Gene:4087 Swiss Prot:P84022 Source:KLH conjugated synthesised phosphopeptide derived from human Smad2/Smad3 around the phosphorylation site of Thr8:PF(p-T)PP Purification:affinity purif...
SMAD protein signal transduction positive regulation of cartilage development positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus Mullerian duct regression transcription, DNA-templated protein phosphorylation germ cell development erythrocyte...
Inhibitory effects of oxyresveratrol on ERK and Smad1/2 phosphorylation and HSC activation in preventing carbon tetrachloride-induced rat liver fibrosis Guliang Yanga, Jianfeng Zhanb,*, Yiwen Yangb, Li Yuanb, Peilei Wangb, Chi-Tang Hoc, Shiming Lib,c,* ...
L. et al. A tissue-specific atlas of mouse protein phosphorylation and expression. Cell 143, 1174–1189 (2010). Article CAS PubMed PubMed Central Google Scholar Du, P., Kibbe, W. A. & Lin, S. M. lumi: a pipeline for processing Illumina microarray. Bioinformatics 24, 1547–1548 (...
In this report, it is demonstrated that exposure of endothelial cells to hypoxia (1% O2) increases messenger RNA and protein levels of transforming growth factor-β2 (TGF-β2), a cytokine with potent regulatory effects on vascular inflammatory responses. Messenger RNA levels of the TGF-β2 ...
上海沪震实业有限公司生产的Smad3 细胞信号转导分子SMAD3单克隆抗体,最新报价:1138元/ul,MouseAnti-Smad3MonoclonalAntibodyDATASHEETHost:MouseTargetProtein:Smad3IR:Immuno