Two Cases of Breast Cancer Presented with Skin Metastasis as First SignsZindancı, İlkinCan, BurçeZemheri, EbruKavala, Mukaddes
Melanoma is staged according to thickness, ulceration, lymph node involvement, and the presence of distant metastasis. The staging of cancer refers to the extent to which it has spread at the time of diagnosis, and staging is used to determine the appropriate treatment. Stages 1 and 2are con...
Cutaneous melanoma is the noxious form ofskin cancer. Assumed to arise from epidermal melanocytes, melanoma is often a treatment refractory and metastasis-prone malignancy, whose incidence has amplified gradually and notably in the past few decades (D'Orazio et al., 2013; Narayanan et al., 2010...
Lung cancer is one of the most common cancers in America. Frequent sites of metastasis include the Hilar lymph nodes, adrenal glands, liver, brain, and bone. The following case report is of a primary lung cancer with metastases to the breast and skin. Ca
This article reviews the formation of melanoma, the molecular events involved in melanoma growth and metastasis, and the biology underlying resistance to melanoma therapies. View article Non-Invasive Technologies for the Diagnosis and Management of Skin Cancer Alex M. Glazer MD, ... Aaron S. ...
Lo PK. The controversial role of forkhead box F2 (FOXF2) transcription factor in breast cancer. PRAS Open. 2017;1:009. PubMed PubMed Central Google Scholar Lo PK, Lee JS, Liang X, Sukumar S. The dual role of FOXF2 in regulation of DNA replication and the epithelial-mesenchymal transi...
Mclassification: spread of the cancer to other organs (metastasis) Depending on each of the T, N, and M classifications, the cancer is given a “stage” from 0 (pre-cancerous; best prognosis) to IV (most progressive, most difficult to treat). Each type of cancer has its own TNM syste...
Loss of the Par3 polarity protein promotes breast tumorigenesis and metastasis. Cancer Cell. 2012;22:601–14. Article PubMed PubMed Central CAS Google Scholar Guyer RA, Macara IG. Loss of the polarity protein Par3 activates Stat3 signaling via an aPKC/NF-κB/IL-6 axis in mouse mammary ...
SIRT6 drives epithelial-to-mesenchymal transition and metastasis in non-small cell lung cancer via snail-dependent transrepression of KLF4 J. Exp. Clin. Cancer Res., 37 (1) (2018), Article 323 Google Scholar [46] X.M. Li, S.J. Kim, D.K. Hong, K.E. Jung, C.W. Choi, Y.J. ...
Cancer Cell 16, 521–532. https://doi.org/10.1016/j.ccr.2009.10.018 (2009). Article CAS PubMed PubMed Central Google Scholar Wu, Z. et al. MFAP5 promotes tumor progression and bone metastasis by regulating ERK/MMP signaling pathways in breast cancer. Biochem. Biophys. Res. Commun. ...