a, Schematic diagram of the current understanding concerning the general categories of muscle fibers and their respective nuclei. Illustration was created with BioRender.com.b,c, Immunfluorescence staining (b) and proportional changes (c) of different MF types in human intercostal muscles (seven young...
Several previous lineage labeling models have reported labeling of progenitor-enriched, bone marrow MSC populations, however, with the exception ofPrx1-Cre, which labels the entire limb lateral plate mesoderm9, inducible lineage reporters only mark only a minor proportion of a multipotent, self-renewi...
Fig. 5. Schematic diagram of the role of CTMP in modulating myocellular metabolism in denervation-induced muscle atrophy (Created using Biorender.com). While the anabolic pathways generally reduce activity and protein expression, several proteins are upregulated in degenerating muscle tissue. The protei...
Using this system, we observe clonal regions in the bone, particularly at the growth plate, that encompass bone, cartilage, and stromal tissue but not hematopoietic, adipose, or muscle tissue at all time points studied (Figures 1A, 1C–1D, and S1D). These data indicate that bone, ...
hypermethylated (RED) versus hypomethylated (GREEN) signature compared with young adult tissue. (b)CpG sites for most significantly enriched GO term containing the search term ‘muscle’; ‘regulation of muscle system process’ (RED hypermethylated and GREEN hypomethylated CpGs). X axis labels = ...
e Venn diagram comparing “spdNMJ vs extrafusal fiber NMJ” and “spdMTJ vs extrafusal fiber MTJ-B”. Genes enriched in each population (average logFC > 0.7) were used to generate the diagrams. Statistical analysis was performed using hypergeometric test using all genes detected in uninjured/...
(Abbreviations for labels in diagram “a”: b, vertebral body; bm, back musculature; c, vertebral canal; f, fibroadipous tissue in vertebral canal; lm, Vertebral lamina; m, meninges; n, spinal nerve; p, Vertebra pedicle; r, spinal nerve roots; sf, superficial fascia; df, deep fascia;...
the aim of this study was to develop a deep learning-based method for automatic classification of the sagittal skeletal pattern in children and to validate its performance. This would be the first step in establishing a decision support system for early orthodontic treatment. In this study, four...
When utilized by orthopedic surgeons in real clinical scenarios, this AI-powered 3D diagnosis support system could enable a quick and accurate trauma diagnosis. Keywords: YOLO v4; fracture detection; deep learning; three dimensional (3D) reconstructed image; tibia and elbow...