A.Initiation of transcription 1.Overview The frequency of transcription initiation at promoter sequences is dependent on the basal promoter sequence and oncis- andtrans-acting elements that facilitate binding and/or promoter clearance of the RNA polymerase. Described below are examples for both promoter...
RAD26, the yeast homologue of human CSB, has an essential role in transcription-coupled repair (TCR). We have mapped the requisite of Rad26 for nucleotide ... Y Teng,W Raymond - 《Nucleic Acids Research》 被引量: 234发表: 2000年 Crosstalk between mRNA 3' end processing and transcription...
This model is inspired by the interferon-beta (IFN-beta) enhanceosome, which is highly conserved and for which an atomic model of cooperative transcription factor binding has been produced. The billboard model, also known as the information display model, suggests a more flexible architecture for...
predicting DNA-binding sites fromamino acid sequenceswith/without PSSM profiles and developed a Web server called DP-Bind for prediction purposes (http://lcg.rit.albany.edu/dp-bind).Chu et al. (2009)utilizedprotein secondary structureinformation for predicting the binding sites in transcription ...
When the cells are grown in limiting iron concentrations, Irr acts as a repressor for the transcription of the hemB gene encoding one of the heme biosynthetic enzymes, δ-aminolevulinic acid dehydratase, to prevent accumulation of a heme precursor, protoporphyrin IX. In response to cellular ...
Transcription of tyrosine hydroxylase (TH), the ratelimiting enzyme in catecholamine biosynthesis, is regulated in a tissue-specific manner. We have identi... SO Yoon,DM Chikaraishi - 《Neuron》 被引量: 299发表: 1992年 加载更多来源期刊 THE PLANT CELL ONLINE 研究点推荐 Nodule-Infected Cell ...
Human hepatitis B virus infection is characterized by a high degree of hepatotropism which may be due to the dependency of viral genes on specific host factors for their expression. To learn more about such a requirement and the molecular basis of the viral tissue tropism we analyzed the promot...
G Bar-Nahum,E Nudler - 《Cell》 被引量: 196发表: 2001年 Structure and function of the initially transcribing RNA polymerase II–TFIIB complex The general transcription factor (TF) IIB is required for RNA polymerase (Pol) II initiation and extends with its B-reader element into the Pol II ...
Transgenes introduced into cancer cell lines serve as powerful tools for identification of genes involved in cancer. However, the random nature of genomic integration site of a transgene highly influences the fidelity, reliability and level of its expression. In order to alleviate this bottleneck, we...
Activation of cell-specific transcription by a serine phosphatase at the site of asymmetric division. Science 270:641–644 - Duncan, Alper, et al. - 1995 () Citation Context ...gene, spoIIIG/sigG (encoding the � G sigma factor), is discussed later. spoIIE is a serine phosphatase ...