The development of single-cell and spatial transcriptomics methods was instrumental in the conception of the Human Cell Atlas initiative, which aims to generate an integrated map of all cells across the human body. These technology advances are bringing increasing depth and resolution to maps of huma...
we performed single-cell RNA sequencing (scRNA-seq) to identify age-related transcriptional changes in a cell type-specific manner within the mouse ovary at 3 and 9 months of age. We chose to analyze 3- and 9-month-old mice because they remain reproductively...
A pan-cancer single-cell transcriptional atlas of tumor infiltrating myeloid cells Cell, Volume 184, Issue 3, 2021, pp. 792-809.e23 Sijin Cheng,…, Zemin Zhang View PDF The anti-cancer immune response in breast cancer: current and emerging biomarkers and treatments Trends in Cancer, Volume ...
HumanPrimaryCellAtlasData 其他的细胞类型注释流程几乎完全一样,如果后续需要个性化分析,只需要提取出自己识别好的类,然后在这些类中继续走标准流程 1-7,之后还是使用点图进行验证,单纯的只是多了个 group.by 参数而已 第三部分结束,准备进入第四部分 第四部分癌细胞识别 这个癌细胞识别略微小复杂,通常的流程是在已...
ovary aging primate oocyte granulosa cell antioxidant gene Introduction The ovary is a critical female reproductive organ, serving as the source of oocytes and major supplier of steroid sex hormones (Rimon-Dahari et al., 2016). Thus, the ovary is indispensable for both the maintenance of female ...
HANGZHOU, Feb. 23 (Xinhua) -- Chinese scientists have mapped the world's first single-cell mouse cell atlas (scMCA). The research, by a team from Zhejiang University, was published Friday in the Cell journal. Evaluation experts from the journal said the research was of significance to the ...
Tidy R query API for the harmonised and curated CELLxGENE single-cell atlas. - stemangiola/CuratedAtlasQueryR
单细胞测序技术是当下的一个热点,发了不少大文章,逐渐成为 CNS 的标配了。目前,单细胞测序相对来讲还是属于比较昂贵的技术,没钱做不起怎么办? 不用担心,有很多数据库可以用!比如: HCPortalen(网址:http://single-cell.clst.riken.jp),一个人类与小鼠的单细胞测序数据库; ...
Downloadprocessed objectfromCELLxGENEandHuman Cell Atlaswithkey words (filter criteria) Paralleldownload Extract subset with annotation and gene (CELLxGENE) Load the processed object (rds) toSeurat Format conversion and benchmark related tools:
A pan-cancer spatial single-cell transcriptome atlas.aSchematic depicting the study design. The cancer types included in this pan-cancer study were displayed in the first image on the left, created by Figdraw.bThe number of samples in the pan-cancer analysis of scRNA-seq and ST.cPie chart...