Provides Link multivalent peptides Peptides, including liaison with biespecíficos, effector function of immunoglobulin in addition to Coding Nucleic Acids, Vectors and host cells, as well as methods fCALABRO, VALERIEHAYDEN-LEDBETTER, MARTHA SUSAN...
Single-stranded DNA-binding proteins (SSBPs) bind LDB1 and regulate its function (Chen et al., 2002). This family of proteins exerts important roles in embryonic developmental patterning, and hypomorphic alleles of SSBPs have developmental phenotypes resembling that of LDB1 and LMO2 mutants (van...
Single-Strand DNA-Binding Protein refers to a protein that binds to single-stranded DNA, playing a crucial role in protecting, processing, and regulating DNA during replication in various life forms. AI generated definition based on: Encyclopedia of Cell Biology, 2016 ...
Multiple human single-stranded DNA binding proteins function in genome maintenance: structural, biochemical and functional analysis. Crit Rev Biochem Mol Biol 2009; 44:98-116. 2 Flynn RL, Zou L. Oligonucleotide/oligosaccharide-binding fold proteins: a growing family of genome guardians. Crit Rev ...
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The cytidine deaminase, APOBEC3A (A3A), is a prominent source of mutations in multiple cancer types. These APOBEC-signature mutations are non-uniformly distributed across cancer genomes, associating with single-stranded (ss) DNA formed during DNA replica
Structure of the single-stranded-DNA-binding domain of replication protein A bound to DNA THE single-stranded-DNA-binding proteins (SSBs) are essential for DNA function in prokaryotic and eukaryotic cells, mitochondria, phages and viruses 1,2 . ... A Bochkarev,RA Pfuetzner,AM Edwards,... ...
We propose that the DNA binding differences between MCM2-7 and MCM467 correspond to a conformational change at the MCM2/5 active site with putative regulatory significance. 展开 关键词: Saccharomyces cerevisiae DNA Helicases Adenosine Triphosphate DNA, Single-Stranded Nucleotides DNA-Binding Proteins ...
Related to single-stranded DNA:B DNA DNA A. adenine T. thymine C. cytosine G. guanine DNA (dē′ĕn-ā′) n. A nucleic acid that carries the genetic information in cells and some viruses, consisting of two long chains of nucleotides twisted into a double helix and joined by hydrogen ...
function DUF2815. Despite the low (~15%) sequence identity, the Enc34 ORF6 structurally resembles the gene 2.5 protein from bacteriophage T7, and likewise is a single-stranded DNA (ssDNA)-binding protein (SSB) that consists of a variation of the oligosaccharide/oligonucleotide-binding (OB)-...