Single-cell sequencing analyzing the disulfidptosis-related genes expression in cells in BLCA. (a) Cells were grouped and identified and (b) the expression level of disulfidptosis-related genes in different cell clusters. Furthermore, we analyzed the metabolic pathways of different cell subsets....
Identification of a Podocyte-Derived Cytokine as a Potential Mediator of Injury in FSGS via Single-Cell RNA Sequencing of Human Kidney Tissuedoi:10.1681/ASN.20233411S11003dVidhi DalalAnn and Robert H Lurie Children's Hospital of Chicago, Chicago, IL;Yalu Zhou...
10 × Genomics raw sequencing data were processed using CellRanger software (version 3.0.2, 10 × Genomics, Pleasanton, CA), and the 10 × Genomics mouse genome mm10 3.0.0 release was used as the reference genome (function cellranger count). The matrices of cells and the uni...
We analyzed the response of a murine DKD model to five treatment regimens using single-cell RNA sequencing (scRNA-seq). Our atlas of ∼1 million cells revealed a heterogeneous response of all kidney cell types both to DKD and its treatment. Both monotherapy and combination therapies targeted ...
Cell signaling in the neural stem cells, such as the Notch pathway, can be detected in pediatric brain tumors (Lasky and Wu, 2005) and single-cell RNA sequencing of developing human cortex has revealed a diversity of neural stem and progenitor cells with potential roles in neurodevelopmental dis...
Single chain variable fragment (scFv) derived from an antibody used as an extracellular component expressed on the surface of CAR T-cells. It confers antigen specificity and recognizes cancer marker such as human CD19. Sadelain, M. Cell, 171(7), 1471 (2017) A potential strategy for creating...