Single-nucleus RNA sequencingMammalian genomes are pervasively transcribed and a small fraction of RNAs produced codify for proteins. The importance of noncoding RNAs for the maintenance of cell functions is well known (e.g., rRNAs, tRNAs), but only recently it was first demonstrated the ...
single‐cell RNA‐seqQuantitative analysis of singleヽell RNA sequencing (RNA﹕eq) is crucial for discovering the heterogeneity of cell populations and understanding the molecular mechanisms in different cells. In this unit we present a bioinformatics workflow for analyzing singleヽell RNA﹕eq data ...
为了验证鉴定小鼠interneurons的Dlx1/2调控网络,作者分析了人脑的sNuc-Seq(Single nuclei RNA-Seq)数据集。 在人类脑sNuc-Seq数据集上,SCENIC也鉴定出由DLX1/2强烈驱动的interneurons细胞群,该群具有与小鼠相同的motif,并且识别出一组保守的靶标,包括DLX1本身。 接下来,作者将这种跨物种分析扩展到其他细胞类型。与基...
Current best practices in single‐cell RNA‐seq analysis: a tutorialwww.embopress.org/doi/full/10.15252/msb.20188746 单细胞RNA测序(scRNA-seq )是一个飞速发展的领域,该技术帮助科研人员从一堆细胞(bulk)水平精细到单细胞(single-cell)水平研究基因的表达状态,从而可以更加精细的刻画科研对象的分子状态(例...
Learn how Milo detects targets in single-cell sequencing runs and provides single-cell protein expression information to validate single-cell RNA-seq data.
SinglecellRNA-seqdataanalysiswithR CSC – IT科学中心是芬兰国家和高等教育机构拥有的芬兰信息技术专业中心。为高等教育机构,研究机构,文化,公共管理和企业提供国际优质的ICT专家服务,以帮助客户蓬勃发展并造福整个社会。 每年,他们都会在芬兰和国外举办几门有关不同主题的生物信息学课程。 今天分享的课程是Single cell...
first publication a decade ago describing the use of single-cell RNA sequencing (scRNA-seq) in ...
【生信技术】测序数据差异表达分析|导入、加载、整理、分析,RNA-Seq数据的差异分析操作,跟着操作你就对了 231 -- 33:57 App Integrate single-cell RNA-Seq datasets in R using Seurat (CCA) 575 -- 12:56 App (字幕)Single Cell RNA Seqencing(scRNAseq)原理 - Finding a cure for DIPG 1028 -- 9:...
The recent maturation of single-cell RNA sequencing (scRNA-seq) technologies has coincided with transformative new methods to profile genetic, epigenetic, spatial, proteomic and lineage information in individual cells. This provides unique opportunities,
The application of single-cell RNA sequencing (scRNA-seq) in biomedical research has advanced our understanding of the pathogenesis of disease and provided valuable insights into new diagnostic and therapeutic strategies. With the expansion of capacity f