f(2) factorIntersection Union Testprofile similaritysize alpha teststudent's t variableA multivariate test of size a for assessing the similarity of two dissolution profiles is proposed. The inferential procedure is developed by using the approach for the common mean problem in a multivariate setup ...
Bootf2bca and Pheq_bootstrap provided the same f2 and E(f2) also under other truncation rules (EMA or FDA), which are not implemented in DDSolver. Pheq_bootstrap allowed the calculation of bc-f2. The conclusion of similarity is based on a bootstrap percentile CI of E(f2) and f2 in...
2022, 23, 6576 15 of 19 In nonlinear conformers, the crucial factor is the mutual arrangement in space between the R2 substituent (green) and common core (red). In line with moving from nonlinear to linear conformers, a decrease in the descriptor value and an extension of contribution ...