CONCLUSIONS: Low eGFR at baseline predicts poor functional outcome and all-cause mortality at 3-month in acute ICH patients. Also, high cystatin C was associated with increased risk of mortality but not with poor functional outcome. 2016 S. Karger AG, Basel. 展开 关键词: Estimated glomerular ...
Disease-free survival rate was significantly shorter in the cases with high than in the cases with low EGFR levels. These results suggest a potential role of EGFR expression assessment in prognostic characterization of endometrial cancer patients. 漏 1994 Wiley-Liss, Inc.Wiley...
and lung. The altered expression levels of these molecules are closely associated with clinicopathological features, including tumor grade, stage, size, and lymph node metastasis. Elevated or reduced levels of tryptophan metabolism-related molecules reflect the imbalance in tryptophan metabolism that influen...
and lung. The altered expression levels of these molecules are closely associated with clinicopathological features, including tumor grade, stage, size, and lymph node metastasis. Elevated or reduced levels of tryptophan metabolism-related molecules reflect the imbalance in tryptophan metabolism that influen...
Further exploration revealed that KDELR, as a receptor for ER proteins secreted at the cell membrane, has its own downstream signaling network, including trans-activation of the EGFR-STAT3 signaling pathway12. Moreover, accumulating evidence have shown that KDELRs are associated with the development...
Identifying differentially expressed (DE) genes between cancer and normal tissues is of basic importance for studying cancer mechanisms. However, current methods, such as the commonly used Significance Analysis of Microarrays (SAM), are biased to genes with low expression levels. Recently, we proposed...
The levels of COX-2, Ki67, VEGF, CD44V6, EGFR, MDM2 and TGF-β1 protein in nodular growth group and stable group were observed. (b) The correlation between the increase of nodule diameter and the expression level of these proteins was analyzed. Statistical analysis The statistical software...
Phytomedicine. 2023;109:154575. Lu S, Ke S, Wang C, et al. NNMT promotes the progression of intrahepatic cholangiocarcinoma by regulating aerobic glycolysis via the EGFR-STAT3 axis. Oncogenesis. 2022;11(1):39. Article CAS PubMed PubMed Central Google Scholar Download references...
Manabu Ogita1, Takayuki Yokoyama1, Atsushi Amano2 and Hiroyuki Daida1 An equation that accurately estimates the glomerular filtration rate (GFR) in the Japanese population has been proposed; however, the prognostic significance of estimated GFR (eGFR) defined according to this equation has not been...
Lung cancer remains the leading cause of cancer death. Treatment with immune checkpoint inhibitor (ICI) alone or combination with chemotherapy served as first-line therapy in non-small cell lung cancer (NSCLC). However, only 20–50% of NSCLC patients res