Signaling by direct contact is a type of signaling that uses touch to communicate. It's common for infants and their parents or caregivers to use this...Become a member and unlock all Study Answers Start today. Try it now Create an account Ask a question Our experts can answer your to...
by Porcupine (PORCN). Thus, Wnt regulation at homeostasis is regulated by intimate contact with cells situated directly within thestem cell niche. Recent work has also shown that Wnt andHippo signalingregulate each other at the molecular level, connecting Wnt signaling tomechanotransductionand ...
Because of the intricate nature of insulin signaling throughout the body, disruptions in these pathways are associated with various health conditions, including cardiovascular disease, obesity, andtype 2 diabetes. These health problems are characterized by tissues (liver, brain, and adipose) that become...
Signal transduction is based on the need of different cells to communicate with each other in order to coordinate their growth and differentiation. The mechanisms for such complex regulation include secretion of soluble signaling molecules, as well as direct contacts between cells. Signal transduction p...
4. The crosstalk between these signaling pathways can occur through the direct reciprocal antagonism, such as between mTORC1 and AMPK190,207,242 or Akt and LKB1,187 or via indirect inhibition of downstream signaling effectors. For example, the ULK1 complex, which promotes autophagy, is inhibited ...
Baboon females that had been ovariectomized hardly drew the attention of singly housed males when placed in visual, olfactory, and auditory contact with them (Girolami and Bielert 1987). Nonetheless, if the same females were provided with large artificial swellings, then the males became sexually ...
However, direct activation of CBRs by WIN55 was still effective (Fig. 5d, e, blue) indicating that the frequency dependence is likely caused by dendritic mechanisms that involve HCN channels. In line with this, ZD7288 also occluded the increase of astrocytic Ca2+ events triggered by alveus ...
The non-integrated Sentinel product provides external monitoring of SS7 links without direct connection to an EAGLE 5 ISS. In the non-integrated Sentinel, SS7 traffic is processed by a series of processes collectively referred to as a Sentinel Site Collector. A Sentinel Site Collector System ...
The ROS formation process occurs when Fe3+ present in activated LOX is reduced by the contact of this enzyme with its substrate [111]. The leading members of this family include 5-lipooxygenase (5-LOX), 12-lipoxygenase (12-LOX), and 15-lipoxygenase (15-LOX), and this classification is ...
Since insulin-positive cells have to detach and migrate away from the pancreatic ducts to form mature islets, one of the measures of islet cell migration is the degree to which insulin-positive cells remain in direct contact with the ductal epithelium. To assess migration of the endocrine cells...