Physically blocking cell-cell contact or inhibiting PI3K signaling abrogated cell-cell induced proliferation, but inhibiting diffusible paracrine signaling did not. Thus, direct cell-cell contact induces proliferation in these cells. 展开 关键词: Cell shape Microcontact printing Intercellular adhesion ...
Cell-to-cell communication between cancer cells and cells in the bone/BM niche is essential for the survival and growth of tumor cells in bone. The Notch signaling pathway is activated by cell-to-cell contact between adjacent cells and regulates proliferation, apoptosis, and differentiation in mul...
Cell Signaling - ScienceDirectdoi:10.1016/B978-0-12-814371-1.00012-6Randy WaynePlant Cell Biology (Second Edition)
Cellular signaling encompasses the ability of cells to receive, integrate, and react to signals in their surroundings. The field of signal transduction research is vast and complex. This chapter provides a modest introduction using examples of two signaling pathways. The case study, "How Cells Know...
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is correct confirm that number can be dialed on a different system to prove the number is in service and works. You could, for example, dial the number from a cell phone. If the number works outside of this system and is formatted correctly, raise a support is...
2a for examples of the line profiling of CYK-4::GFP intensity). Within the next 30–60 s, the central spindle was established, with CYK-4 enriching rapidly in the central overlap zone and remaining there for ∼300 s until the cleavage furrow fully ingressed and the central spindle ...
(Fig.1) was rarely observed in this study. Interestingly, in the examples shown, labeled synapses are all contained in the head of spines, particularly identifiable in the sagittal section of a spine depicted in Fig.1d. Cortical glutamatergic terminals form asymmetric synapse at the head of ...
The single-cell potential influences and is in turn influenced by the membrane voltage-gated ion channels (Figs. 4–7). However, the above examples clearly show that this fact is complicated further by the intercellular coupling provided by the gap junctions (Fig. 14, top). As a complementary...
These and other less prominentsignal transduction pathwaysare the intracellular effectors of the many signaling events that are necessary for the unfolding of the numerous coordinated programs that guide the orderly progression ofembryonic development. Specific examples involving these signaling pathways are ...