小干扰RNA(Small interfering RNA;siRNA)有时称为短干扰RNA(short interfering RNA)或沉默RNA(silencing RNA),是一个长20到25个___的双股RNA,在生物学上有许多不同的用途。目前已知siRNA主要参与___(RNAi)现象,以带有___的方式调节___的___。此外,也参与一些与RNAi相关的反应途径,例如抗___机制或是___...
小干扰RNA( Small interfering RNA;siRNA)有时称为 短干扰RNA(short interfering RNA)或沉默RNA( silenci
The RNA interference (RNAi) has been suggested to have the potential for implementation in targeted therapy in which the faulty gene can be edited by delivering its complementary Short Interfering RNA (siRNA) at the post-transcriptional stage. The successful editing of a specific gene by the ...
Short interfering RNA (siRNA) and short-hairpin RNA (shRNA) have recently helped extend our understanding of the mechanisms regulating angiogenesis and tumor developments. Moreover, the early success of these tools has reinforced the therapeutic hopes of preventing endogenous or exogenous gene ...
百度试题 题目6.小分子干扰核糖核酸( SIRNA, short interfering RNAS 相关知识点: 试题来源: 解析反馈 收藏
Short-Interfering RNA (siRNA) Reference Work Title Encyclopedia of Nanotechnology Pages p 2411 Copyright 2012 DOI 10.1007/978-90-481-9751-4_100755 Print ISBN 978-90-481-9750-7 Online ISBN 978-90-481-9751-4 Publisher Springer Netherlands Copyright Holder Springer Science+Business Media B.V. Add...
Short interfering RNA (siRNA) is one of the members of the family of RNA interference (RNAi). Coupled with the RNA-induced silencing complex (RISC), siRNA is able to trigger the cleavage of target RNAs which serve as a defensive system against pathogens. Meanwhile, siRNA in gene silencing ...
In RNA interference (RNAi), the RNase III Dicer processes long double-stranded RNA (dsRNA) into short interfering RNA (siRNA), which, when loaded into ARGONAUTE (AGO) family proteins, execute gene silencing. Remarkably, RNAi can act non-cell autonomously: it is graft transmissible, and ...
The development of gene silencing therapies for neurological diseases has placed great importance on the delivery of short interfering RNA (siRNA) to the central nervous system (CNS). However, delivery of siRNA to neurons, glia and brain capillary endothelial cells (BCECs) has not been well estab...
siRNA, short interfering RNA; STAT1, signal transducer and activator of transcription-1; SG, spiral ganglion; SVA, stria vascularis; TACE, TNF-a converting enzyme; TNF-a, tumor necrosis factor-alpha; TRAIL, TNF-related apoptosis inducing ligand; TRPV1, transient receptor vanilloid-1; Tyr701, ...