小干扰RNA(Small interfering RNA;siRNA)有时称为短干扰RNA(short interfering RNA)或沉默RNA(silencing RNA),是一个长20到25个___的双股RNA,在生物学上有许多不同的用途。目前已知siRNA主要参与___(RNAi)现象,以带有___的方式调节___的___。此外,也参与一些与RNAi相关的反应途径,例如抗___机制或是___...
For example, small interfering RNAs (siRNAs) are produced on the basis of sequence complementarity to target and degrade viral RNA, a novel approach to combat viral infections. The precision of siRNAs in targeting and degrading viral RNA has led to the development of siRNA-based treatments for ...
小干扰RNA( Small interfering RNA;siRNA)有时称为 短干扰RNA(short interfering RNA)或沉默RNA( silenci
Small interfering RNA(siRNA):是一种小RNA分子(~21-25核苷酸),由Dicer(RNAase Ⅲ家族中对双链RNA具有特异性的酶)加工而成。SiRNA是siRISC的主要成员,激发与之互补的目标mRNA的沉默。
Small interfering RNA (siRNA), also known as short interfering RNA or silencing RNA, is a kind of non-coding double-stranded RNA containing 21-22 nucleotide base pairs that interfere with the expression of particular genes and mRNA translation by targeting a particular type of gene or mRNA. ...
siRNA small interfering RNA,小干扰 RNA 又称沉默 RNA silencing RNA ,是长度为 20 到 25 个核苷酸的双股 RNA,在生物学上有许多不同的用途。目前已知 siRNA 主要参与 RNA 干扰(RNAi)现象,即干扰了表达与互补的核苷酸序列的特定基因的转录后降解的 mRNA (message RNA
Existing nucleos(t)ide analogues and pegylated interferon exhibit limited efficacy in the functional cure of hepatitis B. Recently, small nucleic acid drugs, such as antisense oligonucleotides and small interfering RNAs, have brought unprecedented b
The invention pertains to using double stranded ribonucleic acid molecules such as small interfering RNA (siRNA) molecules to target an SOD gene to interfere with gene expression and SOD protein production. Method are disclosed for inhibiting expression of a target protein in a subject with a ...
1.3.1 small interfering RNAs (siRNA) Interfering RNA (RNAi), siRNA, and micro RNA (miRNA) have recently been applied to gene therapy in cancer. The siRNA suppress the expression of carcinogenic genes by targeting that of messenger RNA (mRNA). Small interfering RNA (usually 20-24 bp) induces...
(miRNAs), small interfering RNA (siRNAs), piwi-associating RNA (piRNAs), transfer tRNA-derived small RNAs (tsRNAs) and small nucleolar RNAs (snoRNAs) (Wu et al.2022), which are vulnerable to environmental insults, such as unhealthy diet, creating heritable epigenetic memories (Wu et al.2022...