The incidence of coronary artery disease is significantly higher in men than in women, at least until menopause. This gender difference could be explained by the action of sex steroids on the lipoprotein profile. In prepubertal children, high-density lipoprotein (HDL) cholesterol and triglyceride lev...
“SHBG typically circulates at higher concentrations in women than in men, due to the higher ratio of estrogens to androgens in women...” ...relationship to Breast Cancer “It has been reported that women with high levels of sex hormone binding globulin –which reduces the activity of th...
Sex steroids, in particular low bioavailable estradiol and high sex hormone-binding globulin (SHBG), are associated with bone loss and high SHBG is associated with vertebral fractures in older men. We, therefore, hypothesized that low bioavailable estradiol and high SHBG would be associated with ...
SHBG is ordered primarily when the total testosterone results do not seem consistent with clinical signs and symptoms. In men, these may include infertility, decreased sex drive, and erectile dysfunction; in women, examples are infertility, irregular menstrual periods, and excess facial and body hair...
Methods We retrospectively evaluated 169 HIV-infected men with sexual symptoms, with TT available. Among them, we selected 94 patients with TT, SHBG, cFT, and luteinizing hormone (LH) available, and classified hypogonadism into overt (low TT and/or low cFT) and compensated (high LH, normal ...
In premenopausal and older women, high testosterone and estradiol (E2) and low SHBG levels are associated with insulin resistance and diabetes, conditions characterized by low-grade inflammation. The aim of the study was to examine the relationship between SHBG, total testosterone, total E2, and in...
Testicular function has been studied in 3 groups of patients previously treated for malignant disease. Group 1 consisted of 14 men treated by unilateral orchidectomy only for a testicular teratoma (19-52 years). Group 2 consisted of 30 men treated for a testicular seminoma by unilateral orchid...
The objective here was to evaluate the association between sex hormone-binding globulin (SHBG), sex hormones and metabolic syndrome among men. DESIGN AND SETTING: Retrospective analysis on data from the study "Endogenous oestradiol but not testosterone is related to coronary artery disease in men"...
The symptoms of high SHBG vary between men and women. In both, however, it may cause decreased sex drive, infertility, reduced bone and muscle mass, and decreased energy levels.Causes of High SHBG LevelsCauses shown here are commonly associated with high SHBG. Work with your doctor or other...
Whether xenoestrogen SHBG ligands could reach high enough concentrations in the blood to expose humans to any such effect merits further investigation. 展开 关键词: sex hormone-binding globulin (SHBG xenobiotics xenoestrogens steroids environment