Sex steroids, in particular low bioavailable estradiol and high sex hormone-binding globulin (SHBG), are associated with bone loss and high SHBG is associated with vertebral fractures in older men. We, therefore, hypothesized that low bioavailable estradiol and high SHBG would be associated with ...
In premenopausal and older women, high testosterone and estradiol (E2) and low SHBG levels are associated with insulin resistance and diabetes, conditions characterized by low-grade inflammation. The aim of the study was to examine the relationship between SHBG, total testosterone, total E2, and in...
SHBG is ordered primarily when the total testosterone results do not seem consistent with clinical signs and symptoms. In men, these may include infertility, decreased sex drive, and erectile dysfunction; in women, examples are infertility, irregular menstrual periods, and excess facial and body hair...
Ohlsson, Older men with low serum estradiol and high serum SHBG have an increased risk of fractures. J. Bone Miner. Res. 23, 1552–1560 (2008) Article PubMed Google Scholar A.B. Araujo, T.G. Travison, B.Z. Leder, J.B. McKinlay, Correlations between serum testosterone, estradiol,...
“SHBG typically circulates at higher concentrations in women than in men, due to the higher ratio of estrogens to androgens in women...” ...relationship to Breast Cancer “It has been reported that women with high levels of sex hormone binding globulin –which reduces the activity of th...
The incidence of coronary artery disease is significantly higher in men than in women, at least until menopause. This gender difference could be explained by the action of sex steroids on the lipoprotein profile. In prepubertal children, high-density lipoprotein (HDL) cholesterol and triglyceride lev...
Testicular function has been studied in 3 groups of patients previously treated for malignant disease. Group 1 consisted of 14 men treated by unilateral orchidectomy only for a testicular teratoma (19-52 years). Group 2 consisted of 30 men treated for a testicular seminoma by unilateral orchid...
The objective here was to evaluate the association between sex hormone-binding globulin (SHBG), sex hormones and metabolic syndrome among men. DESIGN AND SETTING: Retrospective analysis on data from the study "Endogenous oestradiol but not testosterone is related to coronary artery disease in men"...
Whether xenoestrogen SHBG ligands could reach high enough concentrations in the blood to expose humans to any such effect merits further investigation. 展开 关键词: sex hormone-binding globulin (SHBG xenobiotics xenoestrogens steroids environment
Testosterone, estradiol and progesterone serum blood levels were evaluated by radioimmunoassay (RIA) in men with acute viral hepatitis (VH) A or B during the 1st, 10th and 30th day of hospitalization in the Department of Infectious Diseases of the Medica