Increased blood lactate levels are common in critically ill patients. Some studies revealed its association with prediction of morbidity and mortality. Hence this study was taken up to assess the levels of serum lactate in sepsis and its outcome. Materials and Method: This study comprised of age ...
We hypothesized that serial evaluation of lactate levels with the SOFA score might improve the utility of the SOFA score for predicting in-hospital mortality in patients with sepsis. We evaluated a novel scoring system that used serial SOFA scores and serum lactate levels to predict mortality in p...
biologically compensated for increased lactic acid metabolism27,28. Hyperammonemia is important pathogenesis of hepatic encephalopathy. Moderate grade hyperammonemia activates lactate dehydrogenase-4 and 6-phosphofructo-2-kinase to support increased lactate turnover in the brain slices29, which was consistent ...
摘要: Background Sepsis is a common critical condition caused by the body's overwhelming response to certain infective agents. Many biomarkers, including the serum lactate level, have been used for sepsis...关键词: Sepsis, Lactate, qSOFA, SOFA, Prognosis, MIMIC III ...
333: SERUM LACTATE LEVEL PREDICTS 3-DAY, 30-DAY, AND 1-YEAR MORTALITY IN PATIENTS WITH AND WITHOUT SEPSISShock states are defined by stereotypic changes in well-known physiologic parameters. While these well-known changes provide a convenient entry point into further evaluation of pat...
JAMA Sepsis Website Key Points QuestionDoes the use of a resuscitation strategy targeting normalization of capillary refill time, compared with a strategy targeting serum lactate levels, reduce mortality among patients with septic shock? FindingsIn this randomized clinical trial of 424 patients with earl...
Fibroblast growth factor 23 (FGF23) and insulin-like growth factor binding protein 7 (IGFBP-7) are suggested to be biomarkers for predicting acute kidney injury (AKI). We compared them with proposed AKI biomarker of cystatin C (CysC), and aimed (1) to ex
Infections are the leading cause of HHS (57.1 percent); the most common infection is pneumonia, often gram negative, followed by urinary tract infection and sepsis [31,32]. Other precipi- tating factors include pancreatitis, myocardial infarction, pulmonary embolism, cerebrovascular accident, and ...
In general, blood glucose levels in mg/dL (ADVIA Chemistry XPT®, Siemens, Munich, Germany), the white blood cell count in giga/L (XE 5000 Hematology Analyzer, Sysmex, Norderstedt, Germany), serum lactate level in mmol/L (ADVIA Chemistry XPT®, Siemens, Germany), partial thromboplastin ...
Univariate and multivariate analyses were performed to assess the HR of the covariates for 28-day mortality in patients with septic shock as shown in the Supplementary Table 3. Univariate analysis showed that age, temperature, MAP, SpO2, heart rate, respiratory rate, creatinine, lactate, urinary ...