Although originally identified in the peripheral nervous system, the 5-HT(3) receptor is also ubiquitously expressed in the central nervous system. Sites of expression include several brain stem nuclei and higher cortical areas such as the amygdala, hippocampus, and cortex. On the subcellular level...
Also presented here are some of the prominent features of the recently characterized 5-HT4 receptor. Although pharmacologic similarities have been suggested between 5-HT-M and 5-HT4 receptors (some potent 5-HT3 antagonists are active, with lower potency, at 5-HT4 receptors), it is clear ...
Serotonin (5-hydroxytryptamine) 是 CNS 中的单胺神经递质和内源性5-HT 受体激动剂。它也是儿茶酚 O-甲基转移酶(COMT) 的抑制剂,Ki 值为 44 μM。 规格价格库存数量 1 mg¥ 178现货 5 mg¥ 315现货 10 mg¥ 473现货 25 mg¥ 823现货 ...
Serotonin 是 CNS 中的单胺神经递质和内源性5-HT受体激动剂。Serotonin 也是儿茶酚 O-甲基转移酶 (COMT) 的抑制剂,其Ki值为 44 μM。 该产品由公安部研究所生产,销售、运输全流程受严格监管。MCE 的所有产品仅用作科学研究或药证申报,请您遵守承诺用途,不得违反法律法规规定用于任何其他用途。
Serotonin is a major component of the inflammatory chemical milieu and contributes to the pain of tissue injury via an action on multiple receptor subtypes. Here we studied mice after genetic or pharmacological disruption of the 5-HT3 receptor, an excitatory serotonin-gated ion channel. We demonstr...
The serotonin 5-HT(3) receptor native to rat hippocampal CA1 stratum radiatum interneurons is blocked by Ca(2+) ions in a dose- and voltage-dependent manner, which is reflected by a region of negative slope conductance in the I-V curve. The steep dependence on the extracellular Ca(2+) ...
Several studies, however, have reported on the functional diversity of native 5-HT(3) receptors, which cannot solely be explained on the basis of the 5-HT(3A) and 5-HT(3B) subunits. After our discovery of further putative 5-HT(3) serotonin receptor-encoding genes, HTR3C, HTR3D, and ...
Antidepressants are functional antagonists at the serotonin type 3 (5-HT3) receptordoi:10.1038/sj.mp.4001314Antidepressants are commonly supposed to enhance ... - 《Molecular Psychiatry》 被引量: 0发表: 2003年 5-HT3 receptors: Role in disease and target of drugs Serotonin type 3 (5-HT3) ...
These data show for the first time that the novel 5-HT(3) subunits are able to form heteromeric 5-HT(3) receptors, which exhibit quantitatively different functional properties compared with homomeric 5-HT(3A) receptors. 展开 关键词: Serotonin receptor novel Receptors Human DOI: 10.1124/mol....
血清素受体5A (5-HT5A)抗体英文名字 Serotonin Receptor 5A (5-HT5A) Antibody 供应商 Imgenex 产品货号 IMG-72113 产品报价 ¥6007/0.05mg 产品说明书 点击查看 购买方式 产品新闻 背景资料 应用类型 IHC 免疫原 Ѫ 来源宿主 反应性 H 保存建议 其他 Imgenex ...