The article discusses studies on common sense and antisense. Included are studies on the use of RNAi to deplete the exonucleolytic RNA exosome in human cells, on the asymmetric strand-specific analysis of gene expression, on the sequencing, mapping and quantifying the density of RNA polymerase ...
Antisense RNA foci in the motor neurons of C9ORF72-ALS patients are associated with TDP-43 proteinopathy GGGGCC repeat expansions of C9ORF72 represent the most common genetic variant of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia. We and ot... J Cooperknock,A Higginbottom,MJ...
Using RT-PCR, endogenous antisense RNA was detected in poly(A) RNA isolated from the larval midgut. Since Southern blots indicated a single gene locus, both the antisense RNA as well as the sense mRNA encoding subunit M40 seem to originate from the same gene. 展开 ...
The powerful genetic tools of Saccharomyces cerevisiae have so far been unavailable for the study of RNA interference (RNAi). Efforts to identify key components of the RNAi machinery in this species have proved futile, and the pathway has been assumed lost in all budding yeasts....
Apomixis vs. sexuality differential expression analyses Based on the GTA, we analyzed the expression level of the complete set of sense and antisense transcripts by using the DESeq2 package. Comparisons included:i) a global differential expression analysis (GDEA), in which pairwise comparisons concer...
While RT PCR is a basic method used for the detection and quantification of RNA expression in cells, primer-independent cDNA synthesis can interfere with RT specificity, and may lead to misinterpretation of the results, especially when both sense and antisense RNA are expressed. For accurate interp...
Single-stranded antisense oligonucleotides and double-stranded short-interfering RNA molecules, which specifically mark target transcripts for degradation, are being investigated for their ability to modulate disease processes. In both cases, the targets are RNA transcripts, and not protein; therefore, all...
RNA worldMaking sense of antisense 来自 Nature 喜欢 0 阅读量: 43 作者: FL Louisa 摘要: The powerful genetic tools of Saccharomyces cerevisiae have so far been unavailable for the study of RNA interference (RNAi). Efforts to identify key components of the RNAi machinery in this species have ...
Spatial and temporal expression patterns of the sense and antisense RNA of the bovine PRAMEY2 in adult bovine testis.Spatial and temporal expression patterns of the sense and antisense RNA of the bovine PRAMEY2 in adult bovine testis.TiCheng ChangYang...
sirnas是双滞留转译RNA的19至21个核甘酸的积聚与2至3核苷酸3'在这两个目的。 该股是感mRNA相同的目标,同时在未来市场股是相辅相成的,两者的东街及mRNA感。 翻译结果5复制译文编辑译文朗读译文返回顶部 siRNAs是19到21核苷酸double-stranded RNAs以2到3核苷酸突出物在两3 ′末端。 而antisense子线是补全的对感觉...