Transcript accumulation of senescence-related genes and genes related to photosynthesis in naturally senescingegy1leaves. The percentages of RNA levels shown above the lanes were estimated by comparison with levels found in wild-type corresponding samples taken at 26 days Full size image The influence ...
Senescence-related gene expression levels were transiently increased in subcutaneous adipose tissue during wound healing Senescent cells play beneficial roles in wound healing by expressing SASP factors including PDGF-AA, CCN1, VEGF, and Serpine1, which promote the production of ECM and prevent excessiv...
6c). PHGDH and PKM2 co-regulate the expression of 21 senescence-related genes (Fig. 6d). RT-qPCR confirmed that knockdown of PHGDH and PKM2 significantly reduced the transcription of senescence-associated genes, including SIRT1, HIST1H3H, BMI1, and LAMA1 (Fig. 6e). The transcription of ...
The expression and phylogenetic characteristics of senescence-related genes allow a framework to be constructed of decisive events in the evolution of the senescence syndrome of modern land-plants. Combining phylogenetic, comparative sequence, gene expression and morphogenetic information leads to the conclus...
Pathogen inoculations and treatments with defence-related chemical signals, salicylic acid and methyl jasmonate induced changes in SEN1 transcript levels. Analysis of transgenic plants expressing the SEN1 promoter fused to uidA reporter gene confirmed the responsiveness of the SEN1 promoter to defence-...
The senescence induction by either loss or gain of Rac1 activity was due at least in part to an increase in cellular reactive oxygen species (ROS). rac1 gene deletion caused a compensatory up-regulation of a closely related family member, Rac3, in mouse embryonic fibroblasts, the activity ...
Transgenicomato (Solanum lycopersicum) plants expressingragmentfhe gene encodinghe E1ubunitfhe 2-oxoglutarate dehydrogenaseomplex inhentisenserientationnd ... Araujo,W.,L.,... - 《Plant Cell》 被引量: 83发表: 2012年 Age-related hearing impairment in senescence-accelerated mouse (SAM). The audi...
To extend the shelf life of freshly harvested vegetables and cut flowers, a maize homeobox gene Knotted1 ( kn1 ) was placed under the control of a wound-inducible promoter win3.12 from hybrid poplar ( Populus trichocarpa × P. deltoides ) and introduced into tobacco plants ( Nicotiana tabacum...
Additionally, SMR analysis indicated thatSMAD6, TERT, DDAH2, TP53BP1, NOTCH1, DNMT3B, MAD1L1, SMAD2, andSMAD3methylation levels may have influenced gene expression. Among genes, and as previously stated,DNMT3Bexpression was causally related to prostate cancer.DNMT3Bis implicated in de novo me...
identified APOE and 5q33.3 as loci related to longevity, and suggested four pathways (carbohydrate metabolism, immune response, MAPK signaling, and calcium signaling) [171]. Evidence has demonstrated that genetic and environmental risk factors might influence lifespan and that no one gene can ensure...