This method offers expedient access to protected secondary benzylic alcohol motifs bearing benzyl, pivaloyl, and N,N-diisopropylcarbamoyl protecting groups.doi:10.1021/acs.orglett.6b00911RahmanRoyKarimi-NamiRoyJohnRoyC.RoyTellisRoyGaryRoyA.Roy
It has been described that the catalysis of AAO implies a hydride abstraction from the benzylic position of the alcohol through a stereoselective mechanism [58], which only takes place from the hydrogen in the pro-R position (Fig. 5). In the case of secondary alcohols, this feature implies ...
Benzylic and aliphatic secondary alcohols were enantioselectively incorporated into the crystal and were successfully enantioseparated with up to 86 and 79 % enantiomeric excess (ee), respectively. Selective incorporation of one enantiomer of 2-butanol, which is a small chiral aliphatic alcohol, was...
A C—C cross-coupling of benzylic alcohols with an air-stable, heterogeneous catalyst yields aryl alkyl ketones efficiently.doi:10.1002/chin.201629084JinLab.XuLab.HongmeiLab.YueLab.ShengLab.LiuLab.HanfeiLab.WangLab.YuqunLab.DuLab.John Wiley & Sons, LtdChemInform...
K. Behbahani, "Selective and Efficient Alcoholyses of Allylic, Secondary- and Ter- tiary Benzylic Alcohols in the Presence of Iron (III)," Tetrahedron, Vol. 54, No. 5-6, 1998, pp. 943-948. doi:10.1016/S0040-4020(97)10350-7
In these studies, Pyridinium chlorochromate-Alumina was used for oxidation of secondary alcohols (safryl alcohol and methyleugenyl alcohol) to ketone. The oxidation of safryl alcohol with PCC-Al2O3 followed by purification by potassium bisulfite yields safryl ketone (62,92%). The oxidation of ...
AlcoholAcrylatesEnantioselectiveAqueousLipase Amano AK is found to be extremely efficient catalyst for hydrolytic kinetic resolution of acrylates of secondary alcohols in aqueous phosphate buffer at pH 7.0. Both aliphatic and benzylic secondary alcohols show good to excellent E values. In recent years, ...
Directed Evolution and Computational Modeling of Galactose Oxidase toward Bulky Benzylic and Alkyl Secondary Alcoholsgalactose oxidasealcoholoxidationdirected evolutionhigh throughputmodelingIn the field of alcohol oxidation, galactose oxidase (GOase) is one of the most established enzymes capable of this ...
ChemInform Abstract: Single‐Electron Transmetalation: Protecting‐Group‐Independent Synthesis of Secondary Benzylic Alcohol Derivatives via Photoredox/Nickel Dual Catalysis.doi:10.1002/chin.201643045Rahman Karimi-NamiRoy and Diana Vagelos Lab.John C. Tellis...
Selective and Efficient Alcoholyses of Ailylic,Secondary-and Tertiary Benzylic Alcohols in the Presence of Iron (III). Peyman S,Nasser l,Farahnaz K. B. Tetrahedron . 1998P. Salehi, N. Iranpoor and F. K. Behbahani, "Selective and Efficient Alcoholyses of Allylic, Secondary- and Ter- ...