Since the beginning of the COVID-19 pandemic in 2020 caused by SARS-CoV-2, the question of the origin of this virus has been a highly debated issue. Debates have been, and are still, very disputed and often violent between the two main hypotheses: a natural origin through the "spillover...
Patients were categorized as antibody-positive or antibody-negative according to their first SARS-CoV-2 antibody test in the database. Main Outcomes and Measures Primary end points were post-index diagnostic NAAT results, with infection defined as a positive diagnostic test post-index, measured in ...
Intriguingly, we found that >92% of patients had detectable antibodies on the day of a positive viral RNA test, suggesting that the agglutination antibody test might complement RNA testing for the diagnosis of SARS-CoV-2 infection. Graphical abstract Download: Download high-res image (169KB) ...
SARS-CoV-2 can be detected in a variety of body fluids such as blood saliva, sputum, etc., and different tissues. Most of the biospecimens are collected from the upper respiratory tract by using nasopharyngeal and/or oropharyngeal swabs. Samples should be harvested in a viral transport medium...
The method allows the virus to be detected without needing to extract SARS-CoV-2 genetic ribonucleic acid (RNA) material. It was developed through a partnership among scientists at the National Eye Institute (NEI), the NIH Clinical Centre (CC) and the National Institute of Dental and Craniofaci...
Since viral RNA of SARS-CoV-2 can be detected in feces, and subsequently in sewage, weeks before the onset of illness, extrapolation of viral load together with the other relevant information could help in predicting the trend of infection in a community. The detection of SARS-CoV-2 viral ...
Comparative study of four SARS-CoV-2 Nucleic Acid Amplification Test (NAAT) platforms demonstrates that ID NOW performance is impaired substantially by patient and specimen type.doi:10.1016/J.DIAGMICROBIO.2020.115200Paul R. LephartMichael A. Bachman...
The aim of this study was to analyze the changes in the utilization of SARS-CoV-2 testing, including a shift in the test specimen samples during the early pandemic period to several peaks of infection from January 2020 to June 2022. The results can help us understand how the utilization of...
Specific primers targetingNucleocapsid(N) gene, andRNA-dependent RNA polymerase(RdRp) genes of SARS-CoV-2 were designed for RT-PSR assay. Purified RNA was used for the standardisation of the RT-PSR using in vitro synthesised viral RNA. A simple visual detection of SARS-CoV-2 by the naked ...
K Quicke, E Gallichote, N Sexton, M Young, A Janich, G Gahm, et al. Longitudinal surveillance for SARS-CoV-2 RNA among asymptomatic staff in five Colorado skilled nursing facilities: epidemiologic, virologic and sequence analysis MedRxiv Prepr Serv Heal Sci (2020) 2020.06.08.20125989 Google...