SARS-CoV-2 IgG seropositivity among pregnant women in Accra is high with a boost of SARS-CoV-2 RBD-specific IgG in vaccinated women. Transplacental transfer of anti-SARS-CoV-2 and malarial antibodies was efficient, supporting vaccination of mothers as a strategy to protect infants against SARS...
Recent evidence provided new insights into the complexity of virus–host interactions. SARS-CoV-2 interacts with RAAS network through ACE2 which functions as SARS (SARS-CoV-1 and -2) viral entry point into the host organism. Initially, the spike S protein of SARS-CoV-2 is activated or prim...
This study aimed to identify mutations in the S gene among SARS-CoV-2 sequences collected in the Middle East and North Africa (MENA), focusing on the D614G mutation, that has a presumed fitness advantage. Another aim was to analyze the S gene sequences phylogenetically. Methods: The SARS-...
Coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerges to scientific research and monitoring of wastewaters to predict the spread of the virus in the community. Our study investigated the COVID-19 disease in Bratislava, based ...
SARS-CoV-2Risk analysisHealthcare workersSerologyWhile others have reported severe acute respiratory syndrome-related coronavirus 2(SARS-CoV-2) seroprevalence studies in health care workers (HCWs), we leverage the use of a highly sensitive coronavirus antigen microarray to identify a group of sero...
Therefore, Bebtelovimab seems to be the only EUA antibody broadly neutralizing SARS-CoV-2 and still efficacious against all the VOCs. 4. SARS-CoV-2 and Mechanism of Infection SARS-CoV-2 is a single-stranded RNA-enveloped virus from coronaviruses (CoVs) belonging to the order Nidovirales, ...
SARS-CoV-2 is an enveloped positive-sense RNA virus containing four structural proteins: spike (S), membrane (M), and envelope (E) are membrane bound proteins that surround the ribonucleoprotein complex, composed of nucleocapsid (N) protein bound to viral genomic RNA [7]. The S protein, ...
SARS-CoV-2 is a positive-sense single-stranded RNA (+ssRNA) virus, with a sin- gle linear RNA sequence with ~30,000 nucleotides [10–12]. The SARS-CoV-2 virion is 50–200 nanometers in diameter [6], comprising four structural proteins, known as the S (spike), E (envelope), M ...