Janesch B, Koerdt A, Messner P, Schaffer C. 2013a. The S-Layer homology domain- containing protein SlhA from Paenibacillus alvei CCM 2051T is important for swarming and biofilm formation. PLoS One, 8:e76566.Janesch B, Koerdt A, Messner P, Scha¨ffer C. The S-layer homology domain...
anthracis S-layer homology (SLH) protein harboring a NEAT domain binds and directionally transfers heme to the Isd system via the cell wall protein IsdC. This finding suggests that the Isd system can receive heme from multiple inputs and may reflect an adaptation of B. anthracis to changing ...
ITC isothermal titration calorimetry SapSLH SLH domain trimer from the Bacillus anthracis S-layer protein Sap S-layer surface layer SCWP secondary cell wall polymer SLH-domain surface layer homology domain SpaASLH SLH domain trimer from the Paenibacillus alvei CCM 2051T S-layer protein SpaA ...
PISA67, PDBSum68 and LigPlot+ 69 were used to investigate interdomain and protein-protein interfaces. Structural flexibility of models was assessed by DynDom6D (v1.0 with default settings70), HingeProt webserver71 and the components of DynOmics webserver. Homology models for SLCT ...
Generally, Lactobacillus S-layer proteins are devoid of a surface-layer homology domain that anchors the S-layer to the cell wall peptidoglycan21. Instead, sequences with similarity to tyrosine/phenylalanine-containing carbohydrate-binding motifs or teichoic acid-binding motifs are present in the cell...
2017). The β-barrel bears a high level of structural similarity to the runt homology domain from the RUNX family of eukaryotic transcription factors. The RUNX family of proteins are a group of metazoan transcription factors whose functions can be modulated via a wide range of posttranslational ...
Paenibacillus alvei CCM 2051(T) cells are decorated with a two-dimensional (2D) crystalline array comprised of the glycosylated S-layer protein SpaA. At its N terminus, SpaA possesses three consecutive surface layer (S-layer) homology (SLH) domains containing the amino acid motif TRAE, known ...
Bacillus anthracis synthesizes two S‐layer proteins, each containing three S‐layer homology (SLH) motifs towards their amino‐terminus. In vitro experiments suggested that the three motifs of each protein were organized as a structural domain sufficient to bind purified cell walls. Chimeric genes ...
Physical and genetic char- acterization of an outer-membrane protein (OmpM1) containing an N-terminal S-layer-like homology domain from the phylogenetically Gram-positive gut anaerobe Mitsuokella multacida. Anaerobe. 2009; 15(3):74-81. doi: 10.1016/j.anaerobe.2009.01.001 PMID: 19344649....
domain-containing protein 10 (ADAM10) that is important for regulation of Notch signaling and Aβ metabolism33,45,46. To what extent modulation of M42 protein levels, enzymatic activity or protein–Aβ/protein–proteoglycan interactions might affect Aβ plaque deposition or its downstream consequences...