(2013). The S- layer homology domain-containing protein SlhA from Paenibacillus alvei CCM 2051(T) is important for swarming and biofilm formation. PLoS ONE 8, e76566.Janesch, B., Koerdt, A., Messner, P. & Schaffer, C. The S-layer homology domain-containing protein SlhA from ...
ITC isothermal titration calorimetry SapSLH SLH domain trimer from the Bacillus anthracis S-layer protein Sap S-layer surface layer SCWP secondary cell wall polymer SLH-domain surface layer homology domain SpaASLH SLH domain trimer from the Paenibacillus alvei CCM 2051T S-layer protein SpaA ...
anthracis S-layer homology (SLH) protein harboring a NEAT domain binds and directionally transfers heme to the Isd system via the cell wall protein IsdC. This finding suggests that the Isd system can receive heme from multiple inputs and may reflect an adaptation of B. anthracis to changing ...
Notably, the S-layer homology domain (SLH) responsible for anchoring the S-layer in Bacillus anthracis has a central three α-helical bundle19 similar to the core of the CWB2 triad organisation in SLPH. The HID motif interlocks with LID in an arrangement reminiscent of a paperclip: LID α...
Generally, Lactobacillus S-layer proteins are devoid of a surface-layer homology domain that anchors the S-layer to the cell wall peptidoglycan21. Instead, sequences with similarity to tyrosine/phenylalanine-containing carbohydrate-binding motifs or teichoic acid-binding motifs are present in the cell...
Formin-homology-domain-containing protein FHOD1 is involved in cell migration and adhesion, acting as a regulator of stress fibers organization, maturation of integrin-based adhesion sites, and podosome-associated contractility. >XP_003127395.2 PREDICTED: proline-rich protein 12 isoform X1[Sus scrofa...
Novartis is adding another weapon to its arsenal of oncology therapies, paying Arvinas (New Haven, CT; $1M SBIR in one award) $150 million upfront for rights to a phase 3-ready protein degrader that could treat a wide range of prostate cancer patients. The deal, which is worth up to...
Connected to redox protection are also thirty AAA+type ATPases and three peroxisome assembly factor 2 containing proteins (KOG0736). This broad effort in protein protection is further supported by molecular chaperones (HSP70, mortalins and other; total of 50 proteins) and chaperonin complex ...
Normal epithelium from gingiva or tongue did not stain with each antibody, while an occasional reaction was observed in lympho- cytes that infiltrated into the submucosal layer (Figure 4C). LMO4- and/or LDB1-immunoreactive carcinoma cells were usually found at the periphery of the carcinoma ...
homology-dependent repair system and demonstrated the functionality of gene repair, providing a potential gene therapy for CF patients.7Notably, this therapy has achieved the first successful CRISPR/Cas9 gene-editing case in human-derived organoids.239Since this CRISPR/Cas9-mediated homology-dependent ...