3-Hydroxybutyryl-CoA dehydrogenase is an enzyme that catalyzes the second step in the biosynthesis of n-butanol from acetyl-CoA, in which acetoacetyl-CoA is reduced to 3-hydroxybutyryl-CoA. To understand the molecular mechanisms of n-butanol biosynthesis, we determined the crystal structure of 3-...
protein has been implicated in the development of Alzheimer's disease, and mutations in the gene are the cause of 2-methyl-3- hydroxybutyryl-CoA dehydrogenase deficiency (MHBD). Several alternatively spliced transcript variants have been identified, but the ...
Finally, 3-hydroxyacyl-CoA dehydrogenase would convert S-3-hydroxybutyryl-CoA into acetoacetyl-CoA (Bd1836) [EC 1.1.1.35 (http://www.genome.jp/kegg-bin/show_pathway?bba00650)], which channels into central metabolism, thus explaining the increase in predator progeny after preying on PHB-...
P(3HB-co-LA): Poly(3-hydroxybutyrate-co-lactate) V. natriegens: Vibrio natriegens LA: Lactate PHA: Polyhydroxyalkanoates PLA: Polylactic acid PHB: Polyhydroxybutyrate 3HB-CoA: 3-hydroxybutyryl-CoA phaC*: mutant PHA synthetase phaB: NADPH-dependent acetoacetyl-CoA reductase ph...
中文名称:(S)-3-羟基丁酸 英文名称:(3S)-3-hydroxybutanoic acid CAS No.:6168-83-8 分子式:C4H8O3 分子量:104.1045 如需查看该化合物的详细结构式,mol文件,smile,InChi 请点击:(S)-3-羟基丁酸结构式 下载该化合物MOL文件:(S)-3-羟基丁酸MOL ...
(ETF) and the second pair is generated from the oxidation of 3-hydroxybutyryl-CoA to acetoacetyl-CoA (E0′ = −250 mV) which is directly used to reduce NAD+. The first electron pair have high redox potential (E0′ = −125 mV), which can be only used by the ...
For compounds that are not commercially available (2-methylacetoacetate, 3-hydroxybutyrylcarnitine, 3-hydroxyisovalerylcarnitine and hawkinsin), MS parameters were found and optimised from patient urine samples. First, MS spectra were found online [21], and preliminary MRM transitions were generated....
Many fungal intracellular proteins reflect the regulation of carbohydrate catabolism, such as glyceraldehyde-3-phosphate dehydrogenase (GPD) (A0A1Y0JXL3), pyruvate decarboxylase (PDC) (A0A225XTP6), 3-hydroxybutyryl-CoA dehydrogenase (HBD) (A0A225Y9Q8), and inositol oxygenase (IOX) (A0A225Y7...
进一步建立Illumina Miseq高通量测序方法对大鼠的盲肠内容物细菌的16S rRNA的V3-V4高变区进行测序,使用PICRUSt2预测功能丰度,结果显示ZZCD显著促进了肠道细菌群落中hbd基因的表达,hbd是编码3-羟基丁酰辅酶A脱氢酶(3-hydroxybutyryl-CoA dehydrogenase)的基因,该酶是肠道菌产丁酸代谢通路的一个关键酶.本部分工作验证了...
eutropha, containing genes encoding PHA synthases, acetyl-CoA acetyltransferase and 3-hydroxybutyryl-CoA dehydrogenase in sequence [1]. However, in Halomonas sp. TD01, phaC and phaA, phaB genes were scattered throughout the genome (Table 1, Additional file 8, Table S3). More interestingly, the...